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Investigations regarding the utility of prodigiosenes to treat leukemia
(2013)
Prodigiosenes, possessing a 4-methoxypyrrolyldipyrrin skeleton, are known for their anti-cancer
activity. Structural modification of the C-ring resulted in a series of prodigiosenes that displayed
promising activity against ...
Thionation Reactions of 2-Pyrrole Carboxylates
(RSC, 2016)
An Improved Method for the Synthesis of F-BODIPYs from Dipyrrins and Bis(dipyrrin)s
(Organic Letters, 2012)
An improved methodology for the synthesis of F-BODIPYs from dipyrrins and bis(dipyrrin)s is reported. This strategy employs lithium salts of dipyrrins as intermediates that are then treated with only one equivalent of boron ...
Use of F-BODIPYs as a protection strategy for dipyrrins: optimization of BF2 removal.
(Journal of Organic Chemistry, 2012)
We recently reported the first general method for the deprotection of 4,4-difluoro-4-bora-3a,4a-diaza-s-indacenes (F-BODIPYs) involving a microwave-assisted procedure for the removal of the BF2 moiety, and liberation of ...
Synthesis and Antimalarial Activity of Prodigiosenes
(Organic and Biomolecular Chemistry, 2014)
Several analogues of the natural compound prodigiosin with modified A- and C-rings were synthesised as were some of their tin, cobalt, boron and zinc complexes. The antimalarial activity of these prodigiosenes was evaluated ...
Bis[Pyrrolyl Ru(II)] Triads: a New Class of Photosensitizers for Metal-Organic Photodynamic Therapy
(2020)
A new family of ten dinuclear Ru(II) complexes based on the bis[pyrrolyl Ru(II)] triad scaffold,
where two Ru(bpy)2 centers are separated by a variety of organic linkers, was prepared to evaluate
the influence of the ...