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Investigations regarding the utility of prodigiosenes to treat leukemia
(2013)
Prodigiosenes, possessing a 4-methoxypyrrolyldipyrrin skeleton, are known for their anti-cancer
activity. Structural modification of the C-ring resulted in a series of prodigiosenes that displayed
promising activity against ...
Synthesis and biological evaluation of prodigiosene conjugates of porphyrin, estrone and 4-hydroxytamoxifen
(Bioorganic & Medicinal Chemistry, 2013)
To generate the first series of prodigiosene conjugates, the tripyrrolic skeleton was appended to estrone, tamoxifen and porphyrin frameworks by way of ester linkers and various hydrocarbon chain lengths. The ability of ...