Pharmacy: Recent submissions
Now showing items 21-25 of 25
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A Method for Structure-Activity Analysis of Quorum-Sensing Signaling Peptides from Naturally Transformable Streptococci
(2009-12)Many species of streptococci secrete and use a competence-stimulating peptide (CSP) to initiate quorum sensing for induction of genetic competence, bacteriocin production, and other activities. These signaling molecules ... -
Lipophilic sugar nucleotide synthesis by structure-based design of nucleotidylyltransferase substrates
(2008-02)Structure-based design of alkyl sugar-1-phosphates provides an efficient nucleotidylyltransferase-catalyzed synthesis of a series of new lipophilic sugar nucleotides possessing long or branched alkyl chains, thereby ... -
Structure-activity analysis of quorum-sensing signaling peptides from Streptococcus mutans
(2007-02)Streptococcus mutans secretes and utilizes a 21-amino-acid signaling peptide pheromone to initiate quorum sensing for genetic competence, biofilm formation, stress responses, and bacteriocin production. In this study, we ... -
Antimicrobial Activities of Jadomycin B and Structurally Related Analogues
(2009-03)Natural products are leads for new antibiotics as a result of their structural complexity and diversity. We have isolated a series of structurally related polyketide-derived natural products from Streptomyces venezuelae ... -
Drug Use Management and Policy Residency: A Service-Learning Application
(American Journal of Pharmaceutical Education, 2005)Objectives. To establish, implement, and evaluate a drug use management and policy residency program within the context of a service-learning framework. Design. Residents completed a 4-month term in which they were ...