Antimicrobial Activities of Jadomycin B and Structurally Related Analogues
Jakeman, David L.
Graham, Cathy L.
Reid, Taryn R.
Wentzell, Jason R.
Douglas, Susan E.
MetadataShow full item record
Natural products are leads for new antibiotics as a result of their structural complexity and diversity. We have isolated a series of structurally related polyketide-derived natural products from Streptomyces venezuelae ISP5230. The most active of these jadomycin analogues showed good activity against a variety of staphylococci, including methicillin-resistant Staphylococcus aureus.
Jakeman, David L., Srinivasulu Bandi, Cathy L. Graham, Taryn R. Reid, et al. 2009. "Antimicrobial Activities of Jadomycin B and Structurally Related Analogues." Antimicrobial Agents and Chemotherapy 53(3): 1245-1247.