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dc.contributor.authorJalink, Matthew
dc.date.accessioned2018-04-06T10:41:24Z
dc.date.available2018-04-06T10:41:24Z
dc.identifier.urihttp://hdl.handle.net/10222/73841
dc.description.abstractRespiratory Syncytial Virus (RSV)-hospitalizations have a substantial disease burden during an infant’s first year of life, and long-term consequences such as asthma remain unclear. This study aimed to quantify the incidence rates of RSV-hospitalization in the first year life and asthma during our 5-year individual follow-up, and evaluate the association between asthma and preceding RSV-hospitalization among preterm infants. A retrospective cohort was constructed from population-based databases in Nova Scotia. RSV-hospitalization and potential risk factors were entered into regression models to evaluate their effect on asthma development. In our final cohort of 3,916 prematurely born infants, the incidence rate of RSV-hospitalization was 25/1000 infants. The cumulative incidence rate of asthma in our cohort was 3.7%. Our Cox PH regression model yielded a HR of 1.58 (1.03-2.41). Our Cox PH results support an association between RSV-hospitalization and asthma in preterm infants.en_US
dc.language.isoen_USen_US
dc.subjectEpidemiologyen_US
dc.subjectPediatricsen_US
dc.subjectRespiratory syncytial virusen_US
dc.subjectAsthmaen_US
dc.titleSevere Respiratory Syncytial Virus (RSV) Infection in Preterm Infants and Later Onset of Asthmaen_US
dc.date.defence2018-03-28
dc.contributor.departmentDepartment of Community Health & Epidemiologyen_US
dc.contributor.degreeMaster of Scienceen_US
dc.contributor.external-examinern/aen_US
dc.contributor.graduate-coordinatorDr. Kathleen MacPhersonen_US
dc.contributor.thesis-readerDr. Linda Doddsen_US
dc.contributor.thesis-readerDr. Pantelis Andreouen_US
dc.contributor.thesis-supervisorDr. Joanne Langleyen_US
dc.contributor.ethics-approvalReceiveden_US
dc.contributor.manuscriptsNot Applicableen_US
dc.contributor.copyright-releaseNot Applicableen_US
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