Faculty of Graduate Studies Online Theses
Recent Submissions
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Groundwater-Surface Water Interactions in the Mabou Harbour Drainage Basin and Potential for Harbour Contamination
Groundwater-borne contamination to coastal waters is a growing risk in the Canadian Maritimes region. Groundwater contaminants can enter the marine environment directly as submarine groundwater discharge, or indirectly as ... -
INVESTIGATING THE EFFECT OF AEROBIC EXERCISE ON CORTICOSPINAL EXCITABILITY: A SCOPING REVIEW
Background/Aim: Emerging evidence suggests aerobic exercise (AE) enhances corticospinal excitability (CSE). The aim of this scoping review was to characterize evidence on whether acute AE increases CSE in healthy and ... -
THE PLASMINOGEN RECEPTOR S100A10: STRUCTURE AND FUNCTION STUDIES
The critical role of the fibrinolytic system is the maintenance of vascular patency. Dysregulation ultimately leads to death; an inappropriate activation that causes excessive bleeding, or an inability to clear blood clots, ... -
INVESTIGATING TARGETED DRIVER MUTATIONS AND PD-L1 EXPRESSION FOR IMPROVED THERAPY OF NON-SMALL CELL LUNG CANCER
Most lung cancer patients are diagnosed at an advanced stage, limiting their treatment options to chemotherapy. New therapies that target driver gene mutations, are used to treat patients who have tumours with these ... -
Learning Adaptive Deep Representations for Few-to-Medium Shot Image Classification
In real-world applications, the environment in which a machine learning system is deployed tends to change due to many factors, such as sample selection bias, prior probability mismatch, and domain shift. This makes it ... -
A contribution to the petrology of the Great Dyke of Nova Scotia
A large steeply dipping, quartz-diabase dyke, over 170 miles long and up to 600 feet wide, cuts Paleozoic rocks in southwestern Nova Scotia. The main minerals are labradorite, pyroxene, quartz: alkali-feldspar and accessory ... -
Phase Change Materials for Thermal Energy Storage
Phase change materials (PCM) offer promise for thermal energy storage. PCMs store heat primarily through the enthalpy change of a phase transition, typically melting. A PCM’s melting and crystallization temperatures should ... -
Development and underdevelopment and the rise of trade unionism in the fishing industry of Nova Scotia, 1900-1950
This is a study of the development of capitalism in the fishing industry of Nova Scotia between 1900 and 1950. In particular, it traces the patterns of growth of two intertwined institutions through two distinct periods ... -
Aciniform Spider Silk Proteins: Investigating Solution-State Assembly and the Potential of Silk Nanoparticles as a Drug Delivery Vehicle
Spider and silkworm silks form a wide variety of biomaterials with desirable mechanical properties and biocompatibility. The process of fibrillogenesis from silk solution is not fully understood, but may be dependent on ... -
Characterization of the Cannabis Terpene Myrcene in Joint Pain and Inflammation in a Rat Model of Rheumatoid Arthritis
Rheumatoid arthritis is a progressive inflammatory condition resulting in joint damage and debilitating pain. Current treatments present with variable efficacy and negative side effects, leaving pain management a priority. ... -
Deep Learning-Based Stacking Neural Network and Generative Adversarial Networks for Human Activity Recognition Based on Ambient Sensors
Smart home for healthcare services has acquired more attention since the increasing development of the Internet of Things and the population ageing over the world. Human activity recognition (HAR) is one of the concerns ... -
DDOS DETECTION MODELS USING MACHINE AND DEEP LEARNING ALGORITHMS AND DISTRIBUTED SYSTEMS
Distributed Denial-of-Service (DDoS) attacks are considered to be a major security threat to online servers and cloud providers. Intrusion detection systems have utilized machine learning as one of the solutions to the ... -
Expanding the Scope of Nickel-Catalyzed C(sp2)–N/O Cross-Coupling Reactions Using Tailored Ancillary Ligands
The ubiquity of aryl C–N/O bonds in pharmaceuticals and natural products necessitates the development of robust and selective methodologies to construct such linkages efficiently. Palladium-catalyzed C(sp2)–N/O cross-coupling ... -
The Role of PRP4K as a Tumor Suppressor in Lewis Lung Carcinoma Cells
Although originally identified as a splicing kinase, recent data indicates that pre-mRNA processing factor kinase 4 (PRP4K) may promote metastasis by a partial epithelial-to mesenchymal transition (EMT) phenotype. Thus, ... -
Loss of PRP4K is linked to anoikis resistance and partial epithelial-to-mesenchymal transition
Metastatic disease is the primary cause of cancer-related death, and as a result the metastatic potential of a tumor is an important indicator of patient survival. For tumor cells to metastasize, they must overcome a special ... -
Biomechanics of forward skating in ice hockey
The purpose of this thesis was to conduct a biomechanical analysis of hockey players skating at top speed in a direct line. Fourteen subjects from four different levels of ice hockey competition were chosen for this ...
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