dc.contributor.author | Hutchinson, Edward Wellington. | en_US |
dc.date.accessioned | 2014-10-21T12:34:37Z | |
dc.date.available | 1990 | |
dc.date.issued | 1990 | en_US |
dc.identifier.other | AAINN64397 | en_US |
dc.identifier.uri | http://hdl.handle.net/10222/55175 | |
dc.description | The quantitative genetics of postponed senescence in Drosophila melanogaster were investigated using postponed-senescence stocks created by selection. There was little evidence of non-Mendelian inheritance, inbreeding depression, net directional dominance, or sex-linkage. | en_US |
dc.description | The apparently simple additive inheritance of postponed senescence allowed the use of conventional quantitative genetic estimators for gene number. Assays of 24-hour fecundity, ovary weight, starvation resistance (female and male), and longevity (female and male) did not indicate a small number of loci involved in postponed aging. | en_US |
dc.description | Heritability estimates for early starvation resistance, a character closely related to longevity, revealed abundant genetic variability in selected and control lines, indicating that neither were near fixation. Selection experiments designed to push each of the two sets of lines towards fixation were performed, although a second series of heritability estimates, conducted after cessation of selection response, revealed that fixation had not occurred. | en_US |
dc.description | A genetic analysis was performed on the newly selected lines. Again there was little evidence of non-Mendelian inheritance, inbreeding depression, net directional dominance, or sex-linkage. The results for a second set of gene number experiments on these stocks also did not indicate the action of a single locus postponing senescence. | en_US |
dc.description | Thesis (Ph.D.)--Dalhousie University (Canada), 1990. | en_US |
dc.language | eng | en_US |
dc.publisher | Dalhousie University | en_US |
dc.publisher | | en_US |
dc.subject | Biology, Genetics. | en_US |
dc.title | Quantitative genetics of postponed senescence in Drosophila melanogaster. | en_US |
dc.type | text | en_US |
dc.contributor.degree | Ph.D. | en_US |