Biochemistry and Molecular Biology Faculty Research, Publications and Presentations: Recent submissions
Now showing items 1-20 of 118
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The cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunction
Lysosomal storage diseases (LSDs) are a family of disorders that result from inherited gene mutations that perturb lysosomal homeostasis. LSDs mainly stem from deficiencies in lysosomal enzymes, but also in some non-enzymatic ... -
FACT, the Bur kinase pathway, and the histone co-repressor HirC have overlapping nucleosome-related roles in yeast transcription elongation
Gene transcription is constrained by the nucleosomal nature of chromosomal DNA. This nucleosomal barrier is modulated by FACT, a conserved histone-binding heterodimer. FACT mediates transcription-linked nucleosome disassembly ... -
Mutational analysis of the Prt1 protein subunit of yeast translation initiation factor 3
The Saccharomyces cerevisiae PRT1 gene product Prt1p is a component of translation initiation factor eIF-3, and mutations in PRT1 inhibit translation initiation. We have investigated structural and functional aspects of ... -
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Growth and Cell-Division during Nitrogen Starvation of Yeast Saccharomyces-Cerevisiae
No abstract available. -
Gene-content evolution in discobid mitochondria deduced from the phylogenetic position and complete mitochondrial genome of Tsukubamonas globosa
The unicellular eukaryotic assemblage Discoba (Excavata) comprises four lineages: the Heterolobosea, Euglenozoa, Jakobida and Tsukubamonadida. Discoba has been considered as a key assemblage for understanding the early ... -
Ornithine Decarboxylase Activity and Cell-Cycle Regulation in Saccharomyces-Cerevisiae
No abstract available. -
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Assessing functional divergence in EF-1 alpha and its paralogs in eukaryotes and archaebacteria
No abstract available. -
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U2 and U6 snRNA genes in the microsporidian Nosema locustae: evidence for a functional spliceosome
No abstract available. -