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Ontology Engineering to Model Clinical Pathways: Towards the Computerization and Execution of Clinical Pathways
(IEEE, 2007)
Clinical pathways translate evidence-based recommendations into locally practicable, process-specific algorithms that reduce practice variations and optimize quality of care. Our objective was to abstract practice-oriented ...
Role of polysialylated neural cell adhesion molecule in rapid eye movement sleep regulation in rats
(Federation of European Neuroscience Societies and Blackwell Publishing Ltd (currently Wiley), 2009-12-03)
Recent evidence suggests that synaptic plasticity occurs during homeostatic processes including sleep-wake regulation, although underlying mechanisms are not well understood. Polysialylated neural cell adhesion molecule ...
Inferring functional constraints and divergence in protein families using 3D mapping of phylogenetic information
(2003-01)
No abstract available.
Glycerol production in rainbow smelt (Osmerus mordax) may be triggered by low temperature alone and is associated with the activation of glycerol-3-phosphate dehydrogenase and glycerol-3-phosphatase
(2006-03)
Rainbow smelt (Osmerus mordax) accumulate high levels of glycerol in winter that serves as an antifreeze. Fish were subjected to controlled decreases in water temperature and levels of plasma glycerol, liver metabolites ...
Lateral transfer of a lectin-like antifreeze protein gene in fishes
(2008-07)
Fishes living in icy seawater are usually protected from freezing by endogenous antifreeze proteins (AFPs) that bind to ice crystals and stop them from growing. The scattered distribution of five highly diverse AFP types ...
The freeze-avoidance response of smelt Osmerus mordax: initiation and subsequent suppression of glycerol, trimethylamine oxide and urea accumulation
(2002-05)
Smelt (Osmerus mordax) were maintained at either ambient water temperature or approximately 5 degrees C and various aspects of their freeze-avoidance response were examined from early winter until early spring. Plasma ...