Browsing Faculty of Science by Author "4693a9d8-ffc6-47b2-9271-2e7a2d73b9a7"

Now showing items 1-5 of 5

  • Bis[Pyrrolyl Ru(II)] Triads: a New Class of Photosensitizers for Metal-Organic Photodynamic Therapy 

    Smithen, Deborah A.; Monro, Susan; Pinto, Mitch; Roque III, John; Diaz- Rodriguez, Roberto M.; Yin, Huimin; Cameron, Colin G.; Thompson, Alison; McFarland, Sherri A. (2020)
    A new family of ten dinuclear Ru(II) complexes based on the bis[pyrrolyl Ru(II)] triad scaffold, where two Ru(bpy)2 centers are separated by a variety of organic linkers, was prepared to evaluate the influence of the ...

  • An Improved Method for the Synthesis of F-BODIPYs from Dipyrrins and Bis(dipyrrin)s 

    Lundrigan, Travis; Baker, Alexander E.G.; Longobardi, Lauren E.; Wood, Tabitha E.; Smithen, Deborah A.; Crawford, Sarah M.; Cameron, T. Stanley; Thompson, Alison (Organic Letters, 2012)
    An improved methodology for the synthesis of F-BODIPYs from dipyrrins and bis(dipyrrin)s is reported. This strategy employs lithium salts of dipyrrins as intermediates that are then treated with only one equivalent of boron ...

  • Microwave-assisted reduction of F-BODIPYs and dipyrrins to generate dipyrromethanes 

    Melanson, Jennifer A.; Smithen, Deborah A.; Cameron, T. Stanley (Canadian Journal of Chemistry, 2013)
    The reduction of BODIPYs and dipyrrins to dipyrromethanes, via a reaction involving ethylene glycol and sodium methoxide, is reported. When benzyl alcohol is used in place of ethylene glycol, the addition of 2,4-dinitrop ...

  • Synthesis and Antimalarial Activity of Prodigiosenes 

    Marchal, Estelle; Smithen, Deborah A.; Uddin, Md. Imam; Robertson, Andrew W.; Jakeman, David L.; Vanessa, Mollard; Goodman, Christopher D.; MacDougall, Kristopher S.; McFarland, Sherri A.; McFadden, Geoffrey I.; Thompson, Alison (Organic and Biomolecular Chemistry, 2014)
    Several analogues of the natural compound prodigiosin with modified A- and C-rings were synthesised as were some of their tin, cobalt, boron and zinc complexes. The antimalarial activity of these prodigiosenes was evaluated ...

  • Use of F-BODIPYs as a protection strategy for dipyrrins: optimization of BF2 removal. 

    Smithen, Deborah A.; Baker, Alexander E. G.; Offman, Matthew; Crawford, Sarah M.; Cameron, T. Stanley; Thompson, Alison (Journal of Organic Chemistry, 2012)
    We recently reported the first general method for the deprotection of 4,4-difluoro-4-bora-3a,4a-diaza-s-indacenes (F-BODIPYs) involving a microwave-assisted procedure for the removal of the BF2 moiety, and liberation of ...