Browsing Faculty of Graduate Studies Online Theses by Title
Now showing items 6152-6171 of 7655
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The role of regulatory T and B cells in host responses to Chlamydia genital tract infection
(2016-01-14)The existence of regulatory T and B cells as important cellular entities in immune responses to infection has been established. The focus of this study was to dissect the role of regulatory T and B cells in regulating the ... -
The role of second messenger interactions in the control of androgen production in the mouse Leydig cell.
(Dalhousie University, 1991) -
The role of secretion associate ras-related GTPase 1b in skeletal muscle insulin signaling
(2023-04-24)Dysfunctional branched-chain amino acid (BCAA) catabolism increases intracellular branched-chain keto acids (BCKA), which inhibit insulin signaling. The discovery of Secretion Associated Ras-related GTPase-1B (Sar1b), a ... -
The Role of Sexual Violence in Shaping Women's Understanding of Possibility
(2021-06-16)This thesis examines women’s understandings of the relationship between sexual violence and their expectations for the future. Rooted in an anti-oppressive feminist theoretical framework, this thesis uses narrative inquiry ... -
THE ROLE OF SHARKS IN MARINE ECOSYSTEMS: EVALUATING OVEREXPLOITED MARINE FISH COMMUNITIES TO DETECT LONG-TERM EFFECTS OF PREDATOR REMOVAL
(2010-12-21)Elasmobranchs are among the oldest and most successful predators in the ocean, yet one of the most vulnerable to the direct and indirect effects of fishing. Many populations are rapidly declining around the world, and an ... -
THE ROLE OF SIBLINGS IN PEDIATRIC PAIN
(2018-02-16)Sibling relationships are common and have an important influence on children’s development. While family factors in pediatric pain have received considerable empirical attention, this work has largely focused on parents, ... -
The Role of Stereopsis in Microsurgical Performance on the EYESi Ophthalmic Surgical Simulator
(2019-04-05)There remains a lack of objective evidence on whether stereopsis is necessary for an ophthalmic surgical career. The present study attempts to address this question by evaluating the surgical performance of subjects with ... -
The role of striatal afferents in the response of striatal neurons to dexamphetamine in freely moving animals.
(Dalhousie University, 1984) -
The Role of SUMOylation in the KSHV Kaposin B-MK2 Signaling Axis
(2019-12-16)Kaposi’s sarcoma (KS) is characterized by infection with Kaposi’s sarcoma associated herpesvirus (KSHV), aberrant inflammation and cell spindling. These phenotypes are recapitulated by expression of the viral gene product ... -
The role of temperature in carbon and nitrogen mineralization from selected arable Nova Scotia soils.
(Dalhousie University, 2007) -
The role of the CDP-choline pathway in the anoikis resitance of Ras transformed intestinal epithelial cells
(2012-11-20)Phosphatidylcholine (PC) is an essential component of biological membranes and is synthesized by the CDP-choline pathway under the control of the rate-limiting enzyme CTP:phosphocholine cytidylyltransferase-alpha (CCT?). ... -
THE ROLE OF THE CELL SURFACE PROTEASE RECEPTOR S100A10 IN ACUTE PROMYELOCYTIC LEUKEMIA (APL) AND ITS REGULATION BY RETINOIC ACID THERAPY
(2019-11-28)Acute promyelocytic leukemia (APL), a subtype of acute myeloid leukemia, is characterized by expression of the promyelocytic leukemia-retinoic acid receptor oncoprotein, PML/RARα, which blocks granulocyte differentiation. ... -
Role of the CXCR3 Chemokine Receptor Axis in the Combination of Oncolytic Vesicular Stomatitis Virus Therapy and Natural Killer T Cell Immunotherapy in Melanoma
(2023-03-01)Advanced melanoma is highly metastatic and resistant to chemotherapies, with a 5-year survival rate below 30%. This study investigated Natural Killer T (NKT) cell-based immunotherapy in combination with oncolytic vesicular ... -
The role of the hippocampus in amygdala-kindled fear in male and female rats.
(Dalhousie University, 2005) -
THE ROLE OF THE IL-17 RECEPTOR-A20 AXIS IN TUMOR GROWTH AND TUMOR MICROENVIRONMENT
(2018-09-28)Constitutive activation of NF-κB and JNK is frequently seen in malignancies; however, the underlying mechanisms remain incompletely understood. During my PhD study, I discovered a previously unrecognized role of interleukin ... -
THE ROLE OF THE IL-17/IL-17R AXIS IN BREAST TUMOR GROWTH AND METASTASIS
(2016-11-01)Clinical trials and animal experiments have revealed that chronic inflammation may contribute to all steps of tumor development from initiation, all the way to metastatic progression, predisposing for the development of ... -
The role of the neural cell adhesion molecule in retinal ganglion cell survival and axonal plasticity.
(Dalhousie University, 2007) -
THE ROLE OF THE PHYSICAL IN AUGUSTINE’S RETURN TO GOD IN THE CONFESSIONES
(2019-01-11)The role of the physical in the Trinitarian cosmos of the Confessiones demonstrates the natural capacity of the human to return to God by, and with, physical bodies. The physical is the relative basis and beginning of ... -
The role of the prime minister in Canadian foreign policy: Trudeau, defence, trade and aid.
(Dalhousie University, 1994) -
THE ROLE OF TOLL-LIKE RECEPTOR 2 IN MODULATION OF BREAST MILK COMPONENTS AND ORAL TOLERANCE
(2021-03-11)Food allergy is a common immune-mediated disease of early life that has increased in incidence over the past three decades. The immaturity of the neonatal immune system makes them prone to the development of allergy. Dietary ...