Browsing Faculty of Graduate Studies Online Theses by Title
Now showing items 5976-5984 of 5984
-
Zebrafish Tools To Combat Acute Myeloid Leukaemia – The Nucleoporin 98 kiloDalton—Homeobox A9 (NUP98-HOXA9) Fusion Oncogene Drives Myeloproliferation By Upregulating DNA (Cytosine-5-)-Methyltransferase 1 (dnmt1)
We need to better understand the genetic mechanisms that transform normal blood cells into acute myeloid leukaemia (AML). Overall survival is improving for children and adults with AML, but traditional therapies can be ... -
ZEBRAFISH XENOTRANSPLANTATION AS A PRECLINICAL THERAPEUTIC PLATFORM FOR T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Pediatric T-cell Acute Lymphoblastic leukemia (T-ALL) is a high-risk disease. There is a need for targeted therapies for T-ALL, and techniques to rapidly screen drug candidates and personalize patient therapy. I developed ... -
Zeros and Asymptotics of Holonomic Sequences
(2011-03-30)In this thesis we study the zeros and asymptotics of sequences that satisfy linear recurrence relations with generally nonconstant coefficients. By the theorem of Skolem-Mahler-Lech, the set of zero terms of a sequence ... -
Zeros of Sections of Some Power Series
(2012-08-28)For a power series which converges in some neighborhood of the origin in the complex plane, the zeros of its partial sums often behave in a controlled manner. We give an overview of some of the major results in the study ... -
Zinc-Silicate Glasses for Transarterial Chemoembolization of Hepatocellular Carcinoma
Drug eluting bead transarterial chemoembolization (DEB-TACE) has emerged as the gold standard therapy for patients diagnosed with hepatocellular carcinoma, the second leading cause of cancer-related deaths worldwide. ... -
Zonation of Hydrogen in Kimberlitic and Mantle Olivines: A Possible Proxy for the Water Content of Kimberlite Magmas
(2011-08-25)Volatiles are fundamental to many aspects of kimberlite magmatism. However, the volatile compositions and concentrations are poorly defined. Enrichment of H in kimberlitic olivines, many of which are xenocrysts, suggests ... -
Zur Tragödie und Heiterkeit. Oscar Wildes Salomé - eine heitere Tragödie?
this analysis. First, the definition and key features of tragedy will be discussed, followed by a closer look at the special circumstance of this public literary form after the 17th century in Europe. In relation to Steiner’s ... -
᾿Εγὼ τὸ Αλφα καὶ τὸ Ωμεγα, ἠ ἀρχὴ καὶ τὸ τέλος: Aristotelian Teleology and Christian Eschatology in Origen’s De Principiis (An Eriugenian Reading of Origen)
The central logic of Origen’s De Principiis rests upon the axiom that “the end must be like the beginning.” Despite the importance of this principle, Origen never elaborates upon it, but simply asserts it as the incontrovertible ... -
ῥοπὴ βίου μοι: THE PASSIVE ROUTE TO APOTHEOSIS IN SOPHOCLES' OEDIPUS AT COLONUS
This thesis seeks to demonstrate the necessary role of passivity in Sophocles’ Oedipus at Colonus as a catalyst of Oedipus’ restoration to community, of his ethical innocence and of the renewed personal agency that culminates ...