Browsing Pharmacy by Submit Date
Now showing items 1-20 of 23
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Drug Use Management and Policy Residency: A Service-Learning Application
(American Journal of Pharmaceutical Education, 2005)Objectives. To establish, implement, and evaluate a drug use management and policy residency program within the context of a service-learning framework. Design. Residents completed a 4-month term in which they were ... -
Antimicrobial Activities of Jadomycin B and Structurally Related Analogues
(2009-03)Natural products are leads for new antibiotics as a result of their structural complexity and diversity. We have isolated a series of structurally related polyketide-derived natural products from Streptomyces venezuelae ... -
Lipophilic sugar nucleotide synthesis by structure-based design of nucleotidylyltransferase substrates
(2008-02)Structure-based design of alkyl sugar-1-phosphates provides an efficient nucleotidylyltransferase-catalyzed synthesis of a series of new lipophilic sugar nucleotides possessing long or branched alkyl chains, thereby ... -
Structure-activity analysis of quorum-sensing signaling peptides from Streptococcus mutans
(2007-02)Streptococcus mutans secretes and utilizes a 21-amino-acid signaling peptide pheromone to initiate quorum sensing for genetic competence, biofilm formation, stress responses, and bacteriocin production. In this study, we ... -
A Method for Structure-Activity Analysis of Quorum-Sensing Signaling Peptides from Naturally Transformable Streptococci
(2009-12)Many species of streptococci secrete and use a competence-stimulating peptide (CSP) to initiate quorum sensing for induction of genetic competence, bacteriocin production, and other activities. These signaling molecules ... -
Embryonic lethality in mice lacking the nuclear factor of activated T cells 5 protein due to impaired cardiac development and function
(2011)Nuclear factor of activated T cells 5 protein (NFAT5) is thought to be important for cellular adaptation to osmotic stress by regulating the transcription of genes responsible for the synthesis or transport of organic ... -
Universal intermittent properties of particle trajectories in highly turbulent flows
(2008-06)We present a collection of eight data sets from state-of-the-art experiments and numerical simulations on turbulent velocity statistics along particle trajectories obtained in different flows with Reynolds numbers in ... -
Development and validation of the Chinese version of the Reintegration to Normal Living Index for use with stroke patients
(2011-02)OBJECTIVE: To develop and validate a Chinese version of the Reintegration to Normal Living Index. DESIGN: Descriptive case-series. SUBJECTS: Seventy-five individuals with chronic stroke and 55 age-matched healthy subjects. ... -
Incidence of Deep Vein Thrombosis in Hospitalized Chinese Medical Patients and the Impact of DVT Prophylaxis
(2011)Objective. To evaluate the incidence of deep vein thrombosis in hospitalized Chinese medical patients and the impact of DVT prophylaxis. Methods. All cases of confirmed proximal DVT from 1 January 2005 to 31 December ... -
Development and validation of a sensitive and specific HPLC assay of cladribine for pharmacokinetics studies in rats
(2007)PURPOSE: To develop and validate a sensitive and specific HPLC assay for cladribine (CdA) in plasma for pharmacokinetic studies in rats. METHODS: CdA and the internal standard AZT were purchased from Sigma-Aldrich Chem. ... -
Scale disparity and spectral transfer in anisotropic numerical turbulence
(1996-01)No abstract available. -
Exercise hemodynamic and neurohormone responses as sensitive biomarkers for diltiazem in rats
(2006-05)Purpose. To investigate the potential of exercise hemodyanamic and neurohormone variables as sensitive biomarkers for pre-clinical evaluation of diltiazem (DTZ). Methods. Sprague Dawley (SD) rats were randomly divided ... -
Elastase and Tryptase Govern TNF alpha-Mediated Production of Active Chemerin by Adipocytes
(2012-12)Chemerin is a leukocyte chemoattractant and adipokine with important immune and metabolic roles. Chemerin, secreted in an inactive form prochemerin, undergoes C-terminal proteolytic cleavage to generate active chemerin, a ... -
Evaluating the quality of randomized controlled trials that examine the efficacy of natural health products: a systematic review of critical appraisal instruments
(2009-12)The purpose of this project was to conduct a systematic review to identify instruments designed to evaluate the quality of randomized controlled trials (RCTs) of natural health products (NHPs). Instruments were examined ... -
Evaluating the quality of randomized controlled trials that examine the efficacy of natural health products: a systematic review of critical appraisal instruments
(2009-12)The purpose of this project was to conduct a systematic review to identify instruments designed to evaluate the quality of randomized controlled trials (RCTs) of natural health products (NHPs). Instruments were examined ... -
The relationship between type of drug therapy and blood glucose self-monitoring test strips claimed by beneficiaries of the Seniors' Pharmacare Program in Nova Scotia, Canada
(2008)BACKGROUND: The healthcare expenditure on self-monitoring of blood glucose (SMBG) test strips under the Nova Scotia Seniors' Pharmacare Program (NSSPP) has increased significantly in recent years. The objective of this ... -
Measuring Knowledge Translation Uptake Using Citation Metrics: A Case Study of a Pan-Canadian Network of Pharmacoepidemiology Researchers
(Taylor & Francis, 2016)ABSTRACT Collecting citation metric data is important, as research funders are increasingly demanding impact assessment, but there is limited consensus on the most rigorous and accurate approach. We compared three ... -
Community engaged scholarship to catalyze innovation: a case study of the uptake of portable inhalers for respiratory medication in a pediatric emergency department in Nova Scotia
(Longwoods Publishing, 2016)This commentary, in response to Tamblyn et al. (2016), provides a case study of the uptake of metered-dose inhalers with spacers to deliver respiratory medication in a pediatric emergency department in Nova Scotia. Our ... -
Impact of pharmacists as immunizers on vaccination rates: a systematic review and meta-analysis
(2016)Background: Underutilization of vaccination programs remains a significant public health concern. Pharmacists serve as educators, facilitators, and in some jurisdictions, as administrators of vaccines. Though pharmacists ...
