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Molecular Mechanisms of Reovirus Oncolysis
(2013-02-06)
Mammalian reovirus is a naturally benign virus that preferentially replicates in cancer cells (reovirus oncolysis) and has been tested as a potential cancer therapy in vitro, in vivo and in clinical trials for treating ...
Dynamic Interplay Between Kaposi's Sarcoma-Associated Herpesvirus Latent Proteins in the Control of Oncogene-Induced Senescence
(2012-04-30)
Acute oncogenic stress can activate autophagy and facilitate permanent arrest of the cell cycle through a failsafe mechanism known as oncogene-induced senescence (OIS). Kaposi's sarcoma-associated herpesvirus (KSHV) is the ...