An Examination of the Association Between Prostate Cancer, Lifestyle Factors and Mental Health Outcomes in a Matched Sample of Men from Atlantic Canada

Abstract

This cross-sectional study aims to examine the association between the presence or absence of a lifetime history of prostate cancer (PCa) diagnosis and current mental health outcomes (anxiety and depression) among men in Atlantic Canada. It will also examine the individual contribution of modifiable lifestyle factors (diet, physical activity, sleep, alcohol and smoking) on this association. Using the Atlantic PATH database, logistic regression analyses and pooled sensitivity analyses evaluated these associations. Our target population had 2.39 (95% CI: 1.03, 5.57) higher odds of screening positive for current depressive symptoms. This association was no longer significant when physical activity or smoking were included. Diet, physical activity, sleep or smoking, but not PCa status, resulted in significant associations with screening positive for current anxiety symptoms. This study can inform and support the development of multidisciplinary patient education and empowerment programs to help improve the quality of life of men living with PCa.