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Measurement of Health-Related Quality of Life in Canadians with Neurological Conditions: A Comparison of the SF6D and HUI3

dc.contributor.authorAbel, Hannah
dc.contributor.copyright-releaseNot Applicableen_US
dc.contributor.degreeMaster of Scienceen_US
dc.contributor.departmentDepartment of Community Health & Epidemiologyen_US
dc.contributor.ethics-approvalNot Applicableen_US
dc.contributor.external-examinern/aen_US
dc.contributor.graduate-coordinatorKathleen MacPhersonen_US
dc.contributor.manuscriptsNot Applicableen_US
dc.contributor.thesis-readerDr. Tanya Packer, Dr. Grace Warneren_US
dc.contributor.thesis-supervisorDr. George Kepharten_US
dc.date.accessioned2014-04-04T13:19:41Z
dc.date.available2014-04-04T13:19:41Z
dc.date.defence2014-03-28
dc.date.issued2014-04-04
dc.description.abstractThe objective of this study was to contribute evidence regarding the use of the SF6D and HUI3 in persons with neurological conditions. The data of 776 individuals from the LINC Study was analyzed. The mean utility score of the HUI3 was 0.47 (95% CI 0.45, 0.49) and SF6D was 0.62 (95% CI 0.62, 0.63). Even though the SF6D and HUI3 were sensitive to a variety of HRQoL domains relevant to persons with neurological conditions, they showed only marginal agreement (ICC of 0.41) with a mean utility difference of 0.15 (95% CI 0.13, 0.17). Discordance varied systematically with HRQoL status and was consistent regardless of the participant or impairment characteristics present. Despite sharing a common purpose, the substantial and clinically important differences found between the SF6D and HUI3 cast doubt on whether the utility estimates produced by these instruments are directly comparable or universally valid.en_US
dc.identifier.urihttp://hdl.handle.net/10222/49082
dc.language.isoenen_US
dc.subjectHealth-related quality of lifeen_US
dc.subjectSF6Den_US
dc.subjectHUI3en_US
dc.subjectNeurological conditionsen_US
dc.subjectutilityen_US
dc.subjectdiscordanceen_US
dc.subjectmeasurementen_US
dc.subjectNeruo-QoLen_US
dc.titleMeasurement of Health-Related Quality of Life in Canadians with Neurological Conditions: A Comparison of the SF6D and HUI3en_US

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