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dc.contributor.authorHu, Guoyu
dc.date.accessioned2021-04-01T17:03:05Z
dc.date.available2021-04-01T17:03:05Z
dc.date.issued2021-04-01T17:03:05Z
dc.identifier.urihttp://hdl.handle.net/10222/80327
dc.descriptionThis is the first comprehensive study of the genetics of AD tests in American mink. The estimates of genetic and phenotypic parameters for AD tests traits in mink not only provided insight into the biological basis of these traits but also a valuable reference to develop efficient AD-test-based genetic programs to help mink farmers to cope with the adverse effects of AD. The findings of this thesis provide a potential method to the mink industry to control AD and reduce the economic losses caused by AD, but further studies are required to determine the effectiveness of ELISA-G in mink breeding programs.en_US
dc.description.abstractThe ineffective current methods in controlling Aleutian disease (AD) have urged mink farmers to select AD resilient mink based on some AD tests, however, little is known about their genetic and phenotypic parameters. In this thesis, we estimated the genetic and phenotypic parameters of four AD tests, including two systems of enzyme-linked immunosorbent assay (ELISA), counterimmunoelectrophoresis test (CIEP), and iodine agglutination test (IAT), and their genetic and phenotypic correlations with pelt quality, reproductive performance, packed-cell volume (PCV), and harvest length (HL). Estimated heritabilities (±SE) were 0.39±0.05, 0.61±0.07, 0.11±0.07, and 0.26±0.05 for antigen-based ELISA (ELISA-G), virus capsid protein-based ELISA, CIEP, and IAT, respectively. The ELISA-G had a moderate repeatability (0.58±0.04) and significant (P<0.05) negative genetic correlations (±SE) with reproductive performance traits (from -0.41±0.16 to -0.49±0.12), PCV (-0.53±0.09), and HL (-0.45±0.16). These results indicated that ELISA-G had the potential to be an indicator for genetic selection of AD resilient mink.en_US
dc.language.isoenen_US
dc.subjectMinken_US
dc.subjectAleutian diseaseen_US
dc.subjectGenetic parametersen_US
dc.subjectDisease resilienceen_US
dc.titleGENETIC AND PHENOTYPIC PARAMETERS FOR ALEUTIAN DISEASE TESTS AND THEIR CORRELATIONS WITH PELT QUALITY, REPRODUCTIVE PERFORMANCE, PACKED-CELL VOLUME, AND HARVEST LENGTH IN MINKen_US
dc.date.defence2021-03-26
dc.contributor.departmentFaculty of Agricultureen_US
dc.contributor.degreeMaster of Scienceen_US
dc.contributor.external-examinern/aen_US
dc.contributor.graduate-coordinatorGordon Priceen_US
dc.contributor.thesis-readerFraser Clarken_US
dc.contributor.thesis-readerJanine Grayen_US
dc.contributor.thesis-supervisorYounes Miaren_US
dc.contributor.ethics-approvalReceiveden_US
dc.contributor.manuscriptsNoen_US
dc.contributor.copyright-releaseNoen_US
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