| dc.contributor.author | Colquhoun, David William. | en_US |
| dc.date.accessioned | 2014-10-21T12:35:32Z | |
| dc.date.available | 1994 | |
| dc.date.issued | 1994 | en_US |
| dc.identifier.other | AAINN05157 | en_US |
| dc.identifier.uri | http://hdl.handle.net/10222/55015 | |
| dc.description | In two experiments, schizophrenic patients with and without abnormal involuntary movements (AIMs) were assessed on a broad range of neuropsychological tests. It was predicted that cognitive impairment in AIMs schizophrenia would resemble that of Huntington's disease (HD) given the possibility that a basal ganglia pathology may underlie cognitive impairment in both disorders. In Experiment 1, schizophrenic patients with AIMs (N = 20) and without AIMs (N = 20) were differentiated from non-psychiatric control subjects (N = 20) on certain tests of problem solving/abstract reasoning (Modified Card Sorting Test), verbal fluency (FAS and Semantic Verbal Fluency Tests), and memory (Visual Reproductions and Paired Associate Learning subtests of the Wechsler Memory Scale and Rey-Osterreith Complex Figure Delayed Recall). Schizophrenic patients with AIMs performed significantly poorer than schizophrenic patients without AIMs only on the Judgment of Line Orientation Test, a measure of visuospatial ability. The cognitive impairment of AIMs schizophrenic patients did not resemble the problem solving and memory deficits that are characteristic of HD. To compare the problem solving ability of patients with schizophrenia and HD (N = 10), simplified and standard versions of the Modified Card Sorting Test were administered in Experiment 2. As with Experiment 1, evidence that the cognitive impairment of AIMs schizophrenic patients resembles that of HD patients was not obtained. The results of the present research question the proposal that a basal ganglia pathology underlies cognitive impairment in AIMs schizophrenia. | en_US |
| dc.description | Thesis (Ph.D.)--Dalhousie University (Canada), 1994. | en_US |
| dc.language | eng | en_US |
| dc.publisher | Dalhousie University | en_US |
| dc.publisher | | en_US |
| dc.subject | Health Sciences, Mental Health. | en_US |
| dc.subject | Psychology, Clinical. | en_US |
| dc.title | The neuropsychological differentiation of schizophrenic patients with and without abnormal involuntary movements. | en_US |
| dc.type | text | en_US |
| dc.contributor.degree | Ph.D. | en_US |
