dc.contributor.author | Morgan, Catherine | |
dc.date.accessioned | 2013-11-15T18:16:26Z | |
dc.date.available | 2013-11-15T18:16:26Z | |
dc.date.issued | 2013-11-15 | |
dc.identifier.uri | http://hdl.handle.net/10222/38668 | |
dc.description.abstract | Vitamin D status is assessed with circulating 25-hydroxyvitamin D [25(OH)D].
As some evidence suggests that low vitamin D status adversely affects neonatal health,
this project aimed to determine the association between cord blood 25(OH)D levels and
preterm birth (PTB; <37 weeks gestation), low birthweight (LBW; <2500 grams) and
small for gestational age (SGA; <10th percentile) and to examine the relationship between
maternal 25(OH)D levels during the first trimester of pregnancy and fetal 25(OH)D
levels at birth in a Canadian population.
This nested case-control study used serums, questionnaires and chart reviews
collected in Quebec City. Compared to 25(OH)D concentrations ≥75 nmol/L,
concentrations 37.5-<75, 50-<75, and <75 nmol/L were associated with lower odds of
LBW, PTB and an adverse neonatal composite outcome, and PTB as well as LBW,
respectively. Maternal and neonatal 25(OH)D were correlated (r=0.23, p<0.01; adjusted
r=0.46, p<0.01). This study contributes to evidence for identifying further policy and
research directions. | en_US |
dc.language.iso | en | en_US |
dc.subject | vitamin D, 25(OH)D, preterm birth, low birthweight, small for gestational age, neonatal outcomes | en_US |
dc.title | Cord Blood Vitamin D Status and Neonatal Outcomes in a Birth Cohort in Quebec | en_US |
dc.date.defence | 2013-11-05 | |
dc.contributor.department | Department of Community Health & Epidemiology | en_US |
dc.contributor.degree | Master of Science | en_US |
dc.contributor.external-examiner | n/a | en_US |
dc.contributor.graduate-coordinator | Dr. Kathleen MacPherson | en_US |
dc.contributor.thesis-reader | Dr. Donald Langille | en_US |
dc.contributor.thesis-supervisor | Drs. Linda Dodds and Christy Woolcott | en_US |
dc.contributor.ethics-approval | Received | en_US |
dc.contributor.manuscripts | Not Applicable | en_US |
dc.contributor.copyright-release | Not Applicable | en_US |