Now showing items 1-3 of 3

  • Detecting recombination in evolving nucleotide sequences 

    Chan, Cheong, Robert Beiko, and Mark Ragan. 2006. "Detecting recombination in evolving nucleotide sequences." BMC Bioinformatics 7(1): 412.
    BACKGROUND:Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. These recombination events can be obscured by subsequent residue substitutions, which consequently complicate ...
  • GANN: Genetic algorithm neural networks for the detection of conserved combinations of features in DNA 

    Beiko, Robert, and Robert Charlebois. 2005. "GANN: Genetic algorithm neural networks for the detection of conserved combinations of features in DNA." BMC Bioinformatics 6(1): 36.
    BACKGROUND:The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA structure and flexibility may also play a role ...
  • Phylogenetic identification of lateral genetic transfer events 

    Beiko, Robert, and Nicholas Hamilton. 2006. "Phylogenetic identification of lateral genetic transfer events." BMC Evolutionary Biology 6(1): 15.
    BACKGROUND:Lateral genetic transfer can lead to disagreements among phylogenetic trees comprising sequences from the same set of taxa. Where topological discordance is thought to have arisen through genetic transfer events, ...