Alan A. Doucette

Associate Professor


Recent Submissions

  • Automated SDS depletion for mass spectrometry of intact membrane proteins through transmembrane electrophoresis 

    Kachuk C, Faulkner M, Liu F, Doucette AA. Automated SDS Depletion for Mass Spectrometry of Intact Membrane Proteins though Transmembrane Electrophoresis. J Proteome Res. 2016 Aug 5;15(8):2634-42. doi: 10.1021/acs.jproteome.6b00199. Copyright © 2016 American Chemical Society after peer review.
    Membrane proteins are underrepresented in proteome analysis platforms because of their hydrophobic character, contributing to decreased solubility. Sodium dodecyl sulfate is a favored denaturant in proteomic workflows, ...