Pediatrics Faculty Research, Publications and Presentations
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Cesarean Delivery and Healthcare Utilization and Costs in the Offspring: A Retrospective Cohort Study
Objective: To examine the association between Caesarean section (CS) and health care utilization and costs in offspring from birth until age 7 years. Methods: A retrospective cohort study of singleton term births in the ... -
Maternal pre-pregnancy weight status and health care use for mental health conditions in the offspring
Objectives: The objective of this study was to examine the relationship between pre-pregnancy maternal weight status and offspring physician visits for mental health conditions in childhood and adolescence. Methods: We ... -
Birth weight for gestational age and the risk of asthma in childhood and adolescence: a retrospective cohort study
Objective: To examine the association between birthweight for gestational age and asthma in childhood and adolescence while controlling for potential confounders and considering smoking as an effect modifier. Methods: A ... -
Faster access to new drugs: Fault lines between Health Canada’s regulatory intent and Industry innovation practices
Since 2003, Health Canada has been undergoing regulatory modernization to “ensure that Canadians have faster access to the safe drugs they need.” As national health agencies develop policies to modernize the regulation ... -
Just Evidence: Opening Health Knowledge to a Parliament of Evidence
In this chapter, we present a complementary perspective to the oceans theme of this volume by ethnographically engaging the circulation of scientific knowledge and evidence in a different but comparable policy decision-making ... -
Risks of nutrigenomics and nutrigenetics? What the scientists say.
Nutrigenomics and nutrigenetics (hereafter NGx) have stimulated expectations for beneficial applications in public health and individuals. Yet, the potential achievability of such promise is not without socioethical ... -
Exploring the post-genomic world: differing explanatory and manipulatory functions of post-genomic sciences
Richard Lewontin proposed that the ability of a scientific field to create a narrative for public understanding garners it social relevance. This article applies Lewontin’s conceptual framework of the functions of science ... -
Ambiguous Capture: Collaborative Capitalism and the Meningitis Vaccine Project
The primary health care approach advanced at Alma Ata to address social determinants of health was replaced by selective health care a year later at Bellagio. Subsequently, immunization was endorsed as a cost-effective ... -
Understanding vaccine hesitancy in Canada: Results of a consultation study by the Canadian Immunization Research Network
“Vaccine hesitancy” is a concept now frequently used in vaccination discourse. The increased popularity of this concept in both academic and public health circles is challenging previously held perspectives that individual ... -
Lueurs et leurres de la santé globale À propos de MenAfriVac®, un vaccin « africain » contre la méningite
In biomedical narratives, the Meningitis Vaccine Project (MVP) enabled the technology transfer for the development and implementation of MenAfriVac® vaccine at an affordable price for African countries. The presentation ... -
Do health care providers trust product monograph information regarding use of vaccines in pregnancy? A qualitative study
Background: In uenza immunization is recommended in pregnancy to prevent severe infections in pregnant women and newborns, yet vaccine uptake remains low. Studies suggest that cautionary language in vaccine product monographs ... -
Frailty, fitness and late-life mortality in relation to chronological and biological age
Background: People age at remarkably different rates, but how to estimate trajectories of senescence is controversial. Methods: In a secondary analysis of a representative cohort of Canadians aged 65 and over (n = 2914) ... -
The clinical meaningfulness of ADAS-Cog changes in Alzheimer’s disease patients treated with donepezil in an open-label trial
Background: In 6-month anti-dementia drug trials, a 4-point change in the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) is held to be clinically important. We examined how this change compared with ... -
Assessment of factors associated with complete immunization coverage in children ages 12-23 months: A cross sectional study in Nouna district, Burkina Faso
Background: The Expanded Program on Immunization (EPI) is still in need of improvement. In Burkina Faso in 2003, for example, the Nouna health district had an immunization coverage rate of 31.5%, compared to the national ... -
Rendre évident: une approche symétrique de la réglementation des produits thérapeutiques
ENGLISH: Within the social studies of science, risk regulation regimes dominated by a technocratic approach are critiqued for neglecting public, socially situated epistemological standpoints, which, it is argued, are more ... -
Global challenges of implementing human papillomavirus vaccines
Human Papillomavirus vaccines are widely hailed as a sweeping pharmaceutical innovation for the universal benefit of all women. The implementation of the vaccines, however, is far from universal or equitable. Socio- ... -
Challenges to immunization: the experience of homeless youth
Background: Homelessness is a critical social issue, both a product of, and contributing to, poor mental and physical health. Over 150,000 young Canadians live on the streets. Homeless youth experience a high incidence of ... -
Substitute Decision Making About Research: Identifying the Legally Authorized Representative in Four Canadian Provinces
Canada's aging population presents new incentives for research on Alzheimer's and other forms of dementia. But the public interest in advancing knowledge about these diseases must be partnered with a concern for exploitation, ... -
Prepared for the “unexpected”? Lessons from the 2014-16 Ebola epidemic in West Africa on integrating emergent theory designs into outbreak response.
Summary Box 1. Even seemingly straightforward interventions, such as vaccine delivery, require real-time awareness of emergent on-the-ground local (‘field’) realities. 2. Outbreak response requires thoughtful engagement ... -
Technologies of trust in epidemic response: openness, reflexivity and accountability during the 2014-2016 Ebola outbreak in West Africa
Trust is an essential component of successful cooperative endeavours. The global health response to the 2014–2016 West Africa Ebola outbreak confronted historically tenuous regional relationships of trust. Challenging ...