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The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study
(2007-01)
No abstract available.
Modelling prokaryote gene content
(2007-02)
The patchy distribution of genes across the prokaryotes may be caused by multiple gene losses or lateral transfer. Probabilistic models of gene gain and loss are needed to distinguish between these possibilities. Existing ...
Ontology Engineering to Model Clinical Pathways: Towards the Computerization and Execution of Clinical Pathways
(IEEE, 2007)
Clinical pathways translate evidence-based recommendations into locally practicable, process-specific algorithms that reduce practice variations and optimize quality of care. Our objective was to abstract practice-oriented ...
Insertions and the emergence of novel protein structure: a structure-based phylogenetic study of insertions
(2007-11)
No abstract available.
Rare group I intron with insertion sequence element in a bacterial ribonucleotide reductase gene
(2007-03)
No abstract available.
The clinical meaningfulness of ADAS-Cog changes in Alzheimer’s disease patients treated with donepezil in an open-label trial
(BMC Springer Nature, 2007-08-30)
Background: In 6-month anti-dementia drug trials, a 4-point change in the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) is held to be clinically important. We examined how this change compared with ...