Browsing Faculty of Graduate Studies Online Theses by Subject "Ubiquitin"
Now showing items 1-4 of 4
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Identification and Characterization of Substrates for the Arabidopsis thaliana RING-type E3 Ligases XBAT32 and KEG
(2016-08-18)The ubiquitin proteasome system (UPS) challenges transcription as the primary regulatory mechanism in the plant kingdom, influencing many cellular processes by selectively degrading proteins. E3 ubiquitin ligases are the ... -
THE ROLE OF THE CELL SURFACE PROTEASE RECEPTOR S100A10 IN ACUTE PROMYELOCYTIC LEUKEMIA (APL) AND ITS REGULATION BY RETINOIC ACID THERAPY
(2019-11-28)Acute promyelocytic leukemia (APL), a subtype of acute myeloid leukemia, is characterized by expression of the promyelocytic leukemia-retinoic acid receptor oncoprotein, PML/RARα, which blocks granulocyte differentiation. ... -
Shigella Effector IpaH9.8 Modulates a Host Ubiquitin-Like Pathway and Lysosomal Biogenesis
(2020-01-21)The bacterium Shigella causes bacterial dysentery in developing countries and represents a persistent burden to healthcare systems due to an increase in antibiotic-resistant strains and lack of a vaccine strategy. Shigella ... -
TOOLS FOR IDENTIFYING FUNCTIONS OF TYPE III SECRETION SYSTEM EFFECTORS FROM SHIGELLA FLEXNERI
(2013-06-18)Shigellae are pathogenic bacteria that cause the disease shigellosis. Two methods for studying secreted effectors encoded by this pathogen’s virulence plasmid are described. First, protein microarrays were used to identify ...