Browsing Faculty of Graduate Studies Online Theses by Subject "HACE1"
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INVESTIGATING THE TUMOUR SUPPRESSING ROLE OF HACE1 AND ITS NOVEL CONTRIBUTION TO CARDIAC DEVELOPMENT USING THE ZEBRAFISH MODEL HACE1 is an E3 ubiquitin-ligase that is epigenetically downregulated in various malignancies. The mechanisms underlying its role in tumourigenesis and in normal vertebrate development have not been well elucidated. We ...