Browsing Faculty of Graduate Studies Online Theses by Subject "Cholesterol"
Now showing items 1-2 of 2
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EXPLORING THE ROLE OF MITOCHONDRIAL CHOLESTEROL IN NIEMANN-PICK TYPE C DISEASE
(2016-01-19)Niemann-Pick type C (NPC) disease is an autosomal recessive neurodegenerative disorder caused by mutations in Npc1 or Npc2 gene. Npc1 and Npc2 encode a late-endosomal transmembrane and lumenal cholesterol-binding domain ... -
THE ROLE OF NPC2 IN CHOLESTEROL TRANSPORT AND THE ENDOCYTIC SYSTEM IN NEUROBLASTOMA CELLS
(2022-04-28)Niemann-Pick type C (NPC) disease is an autosomal recessive, neurodegenerative disorder caused by mutations in either Niemann-Pick Type C1 (NPC1) or NPC2. NPC disease is a lysosomal lipid-storage disease characterized by ...