Browsing Faculty of Graduate Studies Online Theses by Subject "CCR5"
Now showing items 1-2 of 2
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An examination of how Rab GTPases and molecular chaperones influence plasma membrane expression of chemokine receptor dimers
(2013-11-22)Signal termination processes of GPCRs are well established, unlike processes that regulate the assembly and intracellular trafficking of these signaling complexes. Bimolecular fluorescence complementation was used to ... -
INVOLVEMENT OF DIFFERENT RAB GTPASES IN THE TRAFFICKING OF CXCR4 AND CCR5 HOMO- AND HETERODIMERS BETWEEN THE ENDOPLASMIC RETICULUM AND PLASMA MEMBRANE IN HEK293 AND JURKAT CELLS
(2011-08-12)Little is known about the outward trafficking of receptor dimers from the endoplasmic reticulum to the plasma membrane, or the role that trafficking plays in assembly, targeting and specificity of receptor signalling. ...