Browsing Faculty of Graduate Studies Online Theses by Subject "Arrhythmias"
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Cellular and Subcellular Mechanisms of Ventricular Mechano-Arrhythmogenicity
(2021-07-15)The heart is an electro-mechanical pump with feedback mechanisms for responding to acute changes in its mechanical environment. This requires cellular and subcellular elements of cardiac mechano-sensitivity, including ... -
The Contribution of Mechanical Effects to Ventricular Arrhythmias during Acute Regional Ischemia
(2015)Arrhythmias during acute regional ischemia can cause sudden cardiac death. Our goal was to investigate the mechanical contribution to ventricular arrhythmias in this setting. Experiments were conducted in Langendorff-perfused ... -
The Role of Altered Calcium-Handling in Mechanically-Induced Arrhythmias During Acute Regional Ischemia
(2016-06-27)Sudden Cardiac Death, a leading cause of death in Canada, commonly occurs as a result of arrhythmias occurring in the first hour of acute regional ischemia (ARI) after coronary artery occlusion. The mechanisms by which ARI ...