Browsing Faculty of Graduate Studies Online Theses by Title
Now showing items 901-920 of 7638
-
Characterization of Structural and Functional Properties of Class IB Hydrophobins
(2020-08-07)Hydrophobins are low molecular weight self-assembling proteins secreted by fungi and are active at hydrophobic-hydrophilic interfaces. Hydrophobins may undergo structural rearrangement and oligomerize to form rodlets, ... -
CHARACTERIZATION OF THE ANGIOTENSIN TYPE 1 RECEPTOR AND THE BETA2 ADRENERGIC RECEPTOR PROPERTIES: THE INVOLVEMENT OF ARRESTIN2, RAB1 AND SOME MOLECULAR CHAPERONES IN THE ASSEMBLY AND TRAFFICKING OF GPCRS
(2010-09-10)Current drugs used to treat Congestive Heart Failure target the renin-angiotensin and adrenergic systems. Studies showed increased mortality rates in patients treated with a combination of these medications. Angiotensin-AT1 ... -
Characterization of the Arabidopsis thaliana RING-type Ubiquitin Ligase XBAT31.1 and its Role in Response to Iron Deficiency Stress
(2019-11-28)Iron (Fe) is a very important micronutrient, specially for animals and plants. In humans, Fe-deficiency can cause anemia, which affects 43% of children, 38% of pregnant woman and 29% of non-pregnant women (World Health ... -
Characterization of the Cannabis Terpene Myrcene in Joint Pain and Inflammation in a Rat Model of Rheumatoid Arthritis
(2021-01-28)Rheumatoid arthritis is a progressive inflammatory condition resulting in joint damage and debilitating pain. Current treatments present with variable efficacy and negative side effects, leaving pain management a priority. ... -
Characterization of the Diet-Microbiota-Gut-Brain Axis and its Role in Neuroinflammation
(2022-09-01)Neurodegenerative Diseases (NDs) are the leading causes of disability/death globally. The Diet-Microbiota-Gut-Brain (DMGB) axis is a promising area of research for NDs, investigating how intercommunication between diet, ... -
Characterization of the Early Cellular Mechanisms Promoting Myocardial Fibrosis
(2012-08-17)Myocardial fibrosis is a common pathological finding in patients with cardiovascular disease and is believed to be a major contributing factor in the development of end stage organ failure. Early events that promote the ... -
Characterization of the effects of RACK1 expression on mitochondrial physiology
(2023-07-31)Receptor for activated C kinase 1 (RACK1) is a multifunctional scaffolding protein that coordinates a variety of fundamental cellular processes in eukaryotic cells, and its aberrant expression has been implicated in the ... -
Characterization of the gene encoding a 40 kDa major antigen of the sealworm (Pseudoterranova decipiens).
(Dalhousie University, 1994) -
Characterization of the Interaction of Alpha4 Phosphoprotein with Novel Binding Partners: EDD E3 Ubiquitin Ligase and Poly(A)-Binding Protein
(2011-04-08)?4 phosphoprotein (also known as IGBP1) is a component of the mammalian target-of-rapamycin (mTOR) pathway that controls the initiation of translation and cell-cycle progression in response to nutrients and growth factors. ... -
Characterization of the Low- and High-Velocity Impact Performances of Fiber Reinforced Composites with Epoxy and Elium© Based Matrices
(2023-12-12)In recent years, there has been a gradual surge in the demand for fiber-reinforced plastics (FRPs). The implementation of FRPs can be observed across nearly every industry, ranging from advanced applications in aviation ... -
Characterization of the mechanical and hormonal sensitivity of glutamate receptor subtype expression on murine osteoclasts.
(Dalhousie University, 2005) -
Characterization of the mitochondrial genome and ribosomal RNAs of the colorless green alga Polytomella parva.
(Dalhousie University, 2002) -
CHARACTERIZATION OF THE PHOSPHODIESTERASE SUBTYPES THAT REGULATE MOUSE ATRIAL MYOCYTE ELECTROPHYSIOLOGY
(2012-11-20)Phosphodiesterases (PDEs) are the enzymes responsible for the hydrolysis of cyclic nucleotides including cAMP and cGMP. We recently discovered that natriuretic peptides elicit effects in the atrial myocardium via a PDE ... -
Characterization of the roles of neuronal cholesterol biosynthesis and ORP4 in hippocampal neurons and glia
(2018-01-05)Cholesterol is an essential component of cell membranes and plays important roles in cell signalling. The brain contains a quarter of the body’s total cholesterol pool, all of which is synthesized in situ by neurons and ... -
Characterization of The Viable but Non-Culturable Legionella pneumophila in Water and the Role of 3-Hydroxybutyrate Dehydrogenase in Its Formation
(2013-10-03)Legionella pneumophila, the causative agent of Legionnaires’ disease (LD), is an intracellular pathogen of freshwater protozoa that can also persist in the environment as a free-living bacterium. L. pneumophila has many ... -
Characterization of the virulence-related roles of the Legionella pneumophila chaperonin, HtpB, in mammalian cells.
(Dalhousie University, 2007) -
The Characterization of TiC and Ti(C,N) Based Cermets with and without Mo2C
(2014-03-05)Titanium carbide (TiC) and titanium carbonitride (Ti(C,N)) are both common components in hard, wear resistant ceramic-metal composites, or cermets. In this study the intermetallic nickel aluminide (Ni3Al) has been used as ... -
CHARACTERIZING A ROLE FOR NOS1AP IN CELLULAR MECHANOTRANSDUCTION
(2021-08-27)In a screen for proteins that interact with the phosphotyrosine binding (PTB) domain of NOS1AP we identified the b-integrin family of proteins. Fibronectin stimulated mouse embryonic fibroblasts (MEFs) from NOS1AP-/- mice ... -
Characterizing Arsenic Speciation and Metallomic Profiles in Toenail Samples of Atlantic Canadians: A Matched Case-Control Study of Breast, Cervical, Prostate, Urinary, and Skin Cancers
(2020-08-31)Chronic exposure to arsenic and metals has been associated with cancer risk. The research objectives were to 1) characterize the profiles of arsenic speciation and metallomes in the toenails of several cancer groups and ... -
Characterizing Artifact Generated by Passive Medical Devices in Modern Low-Field MRI: A Comparative Evaluation with Routine Clinical Practice
(2023-12-12)Following implantation of a medical device, MRI follow-up imaging is often performed to evaluate device function, assess healing, and monitor treatment progression. Metallic components in devices create artifacts that ...