Browsing Faculty of Graduate Studies Online Theses by Title
Now showing items 3917-3936 of 7892
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INVESTIGATING THE EFFECTS OF DIFFERENT INTENSITIES OF AEROBIC EXERCISE ON CORTICAL EXCITABILITY IN NON-EXERCISED UPPER LIMB MUSCLES OF NON-DISABLED YOUNG ADULTS
(2016-08-22)The goal of rehabilitation after stroke is to achieve functional recovery by driving brain recovery. Research has found that highly excitable brain cells can be stimulated easier than less excitable cells. Aerobic exercise ... -
Investigating the FDA's Appraisal of Preclinical Studies in New Drug Applications for Pain Indications and its Implications for Pepducin P4pal-10
(2023-08-28)Musculoskeletal diseases are responsible for a large proportion of disabling conditions, with chronic pain being the primary concern for patients. Current drug options are limited and often associated with adverse side ... -
Investigating the generation efficiency, growth and structure of flocs produced by electrocoagulation
(2015)Electrocoagulation (EC) is a water treatment technology that releases metal cations into solution from sacrificial anodes. Compared to chemical coagulation (CC), EC’s advantages (e.g., solid metal electrodes, reduced ... -
INVESTIGATING THE GENOMIC COMPOSITION OF OXYRRHIS MARINA, AN EARLY DIVERGING DINOFLAGELLATE
(2024-04-28)Dinoflagellates are microbial eukaryotes with unique nuclear and mitochondrial genome organization. Their nuclear genomes are large and rich in repetitive elements and redundant gene copies, including retrogenes derived ... -
INVESTIGATING THE IMPACTS OF MAST CELLS AND INTERLEUKIN-33 IN RESOLUTION OF INFLAMMATION AND CARDIAC FIBROSIS
(2021-03-16)Cardiac fibrosis is characterized by excessive extracellular matrix deposition and tissue remodeling that leads to heart failure. Chronic inflammation promotes cardiac fibrosis and occurs after initial inflammatory responses ... -
Investigating The Influence Of Attentiveness On Motor Imagery Performance
(2023-11-15)Although much research has focused on motor imagery, the mental rehearsal of movement, little has examined the influence cognitive deficits have on its performance. Recent findings have shown that motor imagery is ... -
INVESTIGATING THE INFLUENCE OF LANDSCAPE DISTURBANCE AND CONNECTIVITY ON HIGH LATITUDE AND ARCTIC AQUATIC SYSTEMS: A PALEOLIMNOLOGICAL APPROACH
(2020-12-15)Connectivity across the terrestrial-aquatic interface drives transport of sediments and nutrients to aquatic systems, a relationship that is significant to historically undisturbed and unproductive lakes. The purpose of ... -
Investigating the integrative role of substrate stiffness, strain, and tone on the functional and phenotypic response of airway smooth muscle in asthmatic airways
(2015-04-30)In recent years, studies have shown that substrate stiffness is a potent modulator of cellular function, gene expression, and morphology in many cell types. These observations may be of important relevance to asthma pathology ... -
Investigating the interactions of bismuth and other metals with biologically relevant molecules.
(Dalhousie University, 2007) -
INVESTIGATING THE MECHANISM OF PROMOTER-SPECIFIC N-TERMINAL MUTANT HUNTINGTIN-MEDIATED TRANSCRIPTIONAL DYSREGULATION
(2012-11-20)Huntington’s disease (HD) is a neurodegenerative disorder caused by the inheritance of one mutant copy of the huntingtin gene. Mutant huntingtin protein (mHtt) contains an expanded polyglutamine repeat region near the ... -
Investigating the Mechanisms that Regulate Differences in Scleral Cartilage Morphology Amongst Teleosts
(2021-08-04)The vertebrate ocular skeleton is comprised of the scleral ossicles and scleral cartilage. The scleral cartilage can vary drastically in morphology across vertebrate taxa, from a cup-like structure in reptiles and birds, ... -
Investigating the Molecular Mechanisms of CBP/p300 Recruitment by the Transcriptional Regulators MITF and β-catenin
(2023-08-11)CREB-binding protein (CBP) and its homolog p300 (CBP/p300) are sequestered by transcription factors to thousands of promoters and enhancers throughout the human genome, where they modify chromatin structure and enhance ... -
INVESTIGATING THE RELATIONSHIP BETWEEN HOUSEHOLD FOOD INSECURITY AND ACADEMIC PERFORMANCE AMONG NOVA SCOTIA ELEMENTARY SCHOOL STUDENTS
(2019-04-29)Background: Education is a fundamental determinant of health, and as such, good academic performance of children has instrumental importance for their health. Household food insecurity, given its association with poor ... -
Investigating the relationship between mammographic breast density and triple negative breast cancer in Nova Scotia, Canada
(2020-04-13)The study objectives were to estimate the association between mammographic breast density (MBD) and triple negative breast cancers (TNBC); as well as to estimate the discriminatory ability of MBD, alone and with clinical ... -
INVESTIGATING THE REMAINING FATIGUE RELIABILITY OF AN AGING ORTHOTROPIC STEEL PLATE DECK
(2014-12-10)The A. Murray MacKay Bridge is an aging structure which opened to traffic over 40 years ago. With many of our structures aging, the ability to make confident management decisions supported by reliable engineering has become ... -
INVESTIGATING THE ROLE OF ACTIVATION-INDUCED CYTIDINE DEAMINASE IN CHLAMYDIA PATHOGENESIS
(2023-06-14)Chlamydia trachomatis is the leading cause of bacterial sexually transmitted infections around the world. The role of antibodies in Chlamydia pathogenesis remains inconclusive. Activation-induced cytidine deaminase (AID) ... -
Investigating the role of frailty in the expression of dementia
(2020-08-28)Background: Frailty is related to neuropathological features of Alzheimer’s disease (AD) as well as cognitive decline and dementia. Objectives: 1) determine whether frailty moderates the relationship between neuropathology ... -
INVESTIGATING THE ROLE OF MLLT11 IN CORTICAL DEVELOPMENT
(2023-08-18)The formation of connections within the mammalian neocortex is highly regulated by both extracellular guidance mechanisms and intrinsic gene expression programs. Dysregulation of these programs has been shown to cause a ... -
INVESTIGATING THE ROLE OF MLLT11 IN SUBVENTRICULAR ZONE NEUROGENESIS AND DEVELOPMENT OF THE OLFACTORY BULB
(2022-08-24)Neurogenesis is the process of generating new neurons in developing and adult brains. This process imparts plasticity to the mammalian brain by allowing novel connections to form and replacing damaged neurons. In later ... -
Investigating the role of MLLT11 in the development of cortical hem derivatives and hippocampal neurogenesis
(2021-03-31)The mammalian Cortical Hem plays a key role in orchestrating the formation of Cajal-Retzius cells, the Choroid Plexus, and hippocampus, a structure crucial to cognition and spatial learning. While several key regulators ...