Browsing Faculty of Graduate Studies Online Theses by Title
Now showing items 6152-6171 of 7666
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Role of Na(v)1.6 and Visual Experience in Retinal and Brain Maturation during the Early Postnatal Period
(2016-08-31)The Scn8a gene encodes the voltage-gated sodium channel isoform Nav1.6, playing a key role in saltatory conduction across the nodes of Ranvier in the CNS. One Scn8a mutation, termed degenerating muscle (dmu) (Scn8admu/dmu) ... -
The Role of NCK in DCC-Sensitive Spinal Cord Circuits
(2016-01-19)Non-Catalytic region of tyrosine Kinase (NCK) adaptor proteins connect cell surface receptors to the actin cytoskeleton. In the central nervous system loss of NCK proteins leads to a hopping like phenotype¬. We were ... -
The role of neuromasts in non-visual feeding of larval striped bass (Morone saxatilis)
(2011-08-03)Striped bass larvae, native to the Shubenacadie River, catch invertebrates in darkness using mechanoreception via lateral line neuromasts. The neuromast total increased from 17 at first feeding (5 to 7 dph) to 135 by the ... -
ROLE OF NEUTROPHIL ELASTASE AND PROTEINASE-ACTIVATED RECEPTOR-2 IN THE JOINT INFLAMMATION AND PAIN ASSOCIATED WITH EXPERIMENTAL ARTHRITIS
(2018-09-28)Arthritis affects many people around the world; it is a leading cause of chronic joint pain, and physical disability. Currently available drug treatments are inadequate and associated with side-effects, so there is a ... -
THE ROLE OF NPC2 IN CHOLESTEROL TRANSPORT AND THE ENDOCYTIC SYSTEM IN NEUROBLASTOMA CELLS
(2022-04-28)Niemann-Pick type C (NPC) disease is an autosomal recessive, neurodegenerative disorder caused by mutations in either Niemann-Pick Type C1 (NPC1) or NPC2. NPC disease is a lysosomal lipid-storage disease characterized by ... -
The Role of Nuclear Architecture in DNA Repair
(2018-09-28)Precise replication of genetic material and the maintenance of genome integrity by DNA repair mechanisms are critical processes in all organisms. The inaccurate repair or accumulation of unrepaired errors can overwhelm the ... -
THE ROLE OF PERSONALITY IN DEFINING THE BOUNDARY BETWEEN PERSUASIVE TECHNOLOGY AND COERCION
(2020-09-01)Persuasive Computing is a sub-discipline of Human Computer Interaction and Com- puter Science. It is focused on motivating users to improve their lives through tech- nological intervention. Examples include fitness ... -
The role of picoplankton in the uptake of inorganic nitrogen in oceanic waters.
(Dalhousie University, 1995) -
The Role of PRP4K as a Tumor Suppressor in Lewis Lung Carcinoma Cells
(2021-01-12)Although originally identified as a splicing kinase, recent data indicates that pre-mRNA processing factor kinase 4 (PRP4K) may promote metastasis by a partial epithelial-to mesenchymal transition (EMT) phenotype. Thus, ... -
The Role of Recurrent Melismas in the Alleluias of the St Gall Cantatorium
(2019-08-30)This thesis studies melodic construction in medieval chant by focusing on the highly melismatic genre of the alleluia. Limiting the corpus to the alleluias found in the tenth century adiastematic St Gall Cantatorium, the ... -
The role of regulatory T and B cells in host responses to Chlamydia genital tract infection
(2016-01-14)The existence of regulatory T and B cells as important cellular entities in immune responses to infection has been established. The focus of this study was to dissect the role of regulatory T and B cells in regulating the ... -
The role of second messenger interactions in the control of androgen production in the mouse Leydig cell.
(Dalhousie University, 1991) -
The role of secretion associate ras-related GTPase 1b in skeletal muscle insulin signaling
(2023-04-24)Dysfunctional branched-chain amino acid (BCAA) catabolism increases intracellular branched-chain keto acids (BCKA), which inhibit insulin signaling. The discovery of Secretion Associated Ras-related GTPase-1B (Sar1b), a ... -
The Role of Sexual Violence in Shaping Women's Understanding of Possibility
(2021-06-16)This thesis examines women’s understandings of the relationship between sexual violence and their expectations for the future. Rooted in an anti-oppressive feminist theoretical framework, this thesis uses narrative inquiry ... -
THE ROLE OF SHARKS IN MARINE ECOSYSTEMS: EVALUATING OVEREXPLOITED MARINE FISH COMMUNITIES TO DETECT LONG-TERM EFFECTS OF PREDATOR REMOVAL
(2010-12-21)Elasmobranchs are among the oldest and most successful predators in the ocean, yet one of the most vulnerable to the direct and indirect effects of fishing. Many populations are rapidly declining around the world, and an ... -
THE ROLE OF SIBLINGS IN PEDIATRIC PAIN
(2018-02-16)Sibling relationships are common and have an important influence on children’s development. While family factors in pediatric pain have received considerable empirical attention, this work has largely focused on parents, ... -
The Role of Stereopsis in Microsurgical Performance on the EYESi Ophthalmic Surgical Simulator
(2019-04-05)There remains a lack of objective evidence on whether stereopsis is necessary for an ophthalmic surgical career. The present study attempts to address this question by evaluating the surgical performance of subjects with ... -
The role of striatal afferents in the response of striatal neurons to dexamphetamine in freely moving animals.
(Dalhousie University, 1984) -
The Role of SUMOylation in the KSHV Kaposin B-MK2 Signaling Axis
(2019-12-16)Kaposi’s sarcoma (KS) is characterized by infection with Kaposi’s sarcoma associated herpesvirus (KSHV), aberrant inflammation and cell spindling. These phenotypes are recapitulated by expression of the viral gene product ... -
The role of temperature in carbon and nitrogen mineralization from selected arable Nova Scotia soils.
(Dalhousie University, 2007)