Browsing Faculty of Graduate Studies Online Theses by Subject "Synthesis"
Now showing items 1-8 of 8
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Design, Synthesis, and Evaluation of Thymidine Derivatives as Inhibitors of a Thymidylyltransferase Enzyme, Cps2L
(2020-08-06)The inhibition of thymidylyltransferase enzymes has long been studied as a potential avenue for antibiotic development. Several thymidine derivatives were designed, synthesized, and evaluated for binding and inhibition ... -
Improved Synthesis and Enhanced Reactivity of X-BODIPYs
(2019-01-15)F-BODIPYs are most known for their high thermal and photochemical stability, being quite chemically robust and having tunable fluorescence properties. This thesis focuses on three general areas of BODIPY chemistry: the ... -
Some Aspects of the Inorganic and Organometallic Chemistry of Dipyrrins
(2020-08-05)Oligopyrroles and their complexes with metals and metalloids are often intensely coloured, and as such, are well-studied as dyes and components of organic light-harvesting systems. Of particular interest in this thesis are ... -
Synthesis and Characterization of Azo bispyrroles
(2023-08-11)Azo dyes are a class of chromophores that can be tuned to access the entire visible range. This characteristic makes azo dyes highly attractive for uses in colouring, and today they account for the majority of industrial ... -
Synthesis of 2-aryl Pyrroles, Prodigiosene F-BODIPYs and B-ring Modified Prodigiosenes
(2019-12-16)Pyrrole constitutes the structural backbone of many natural products including heme and prodigiosin. This tripyrrolic natural product, and its synthetic analogues termed prodigiosenes, are reported to have an impressive ... -
Synthesis of Diazaphospholenes for Improved Catalysis
(2023-08-28)Diazaphospholene (DAP) synthesis and reactivity has been emerging over the last two decades. Recently, DAPs have been employed as catalysts for asymmetric reduction transformations. Specifically in the Speed group we use ... -
Synthesis of Heterocycles via Chemoselective Geminal Acylation of 2-Methoxyoxazolidines, E/Z Isomerization in the Metathesis of Allyl Alcohol Derivatives with a First-Generation Ruthenium Catalyst, and Interception of Nazarov Reaction Intermediates of Allenyl Vinyl Ketones with Arenes
(2013-10-11)Heterocycles were prepared through the geminal acylation of 2-methoxyoxazolidines with 1,2-bis(trimethylsilyloxy)cyclobutene. It was found that when water was excluded from the standard reaction conditions, regioselectivity ... -
Towards the Synthesis of Di- and Tri-Pyrrolic Compounds
(2015)Dipyrrins and prodigiosenes are two classes of pyrrolic compounds. Dipyrrins consist of two pyrrole units linked by a methane bridge and prodigiosenes are a class of pyrrolyldipyrrins (a dipyrrin with a pyrrole substituent) ...