Browsing Faculty of Graduate Studies Online Theses by Subject "Host Shutoff"
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FUNCTIONAL INTERPLAY OF INFLUENZA A VIRUS NS1 AND PA-X PROTEINS MEDIATES HOST SHUTOFF
(2022-11-18)Host shutoff is a mechanism to inhibit gene expression and limit the innate immune response. IAV produces two host shutoff proteins: PA-X and NS1. PA-X is an endonuclease that targets and cleaves host mRNAs. NS1 limits ...