Browsing Faculty of Graduate Studies Online Theses by Subject "Electrophysiology"
Now showing items 1-8 of 8
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Cellular and Subcellular Mechanisms of Ventricular Mechano-Arrhythmogenicity
(2021-07-15)The heart is an electro-mechanical pump with feedback mechanisms for responding to acute changes in its mechanical environment. This requires cellular and subcellular elements of cardiac mechano-sensitivity, including ... -
CHARACTERIZATION OF THE PHOSPHODIESTERASE SUBTYPES THAT REGULATE MOUSE ATRIAL MYOCYTE ELECTROPHYSIOLOGY
(2012-11-20)Phosphodiesterases (PDEs) are the enzymes responsible for the hydrolysis of cyclic nucleotides including cAMP and cGMP. We recently discovered that natriuretic peptides elicit effects in the atrial myocardium via a PDE ... -
Motion Coding Strategies in the Retina
(2013-03-13)Early experimental work suggested that the retina’s main role was to detect changes in brightness and contrast, namely working as a light detector, and that most of the complex computations in the visual system happened ... -
The Perception and Neural Representation of Individual Harmonics in a Vowel Sound: A Behavioral and Auditory Brainstem Evoked Response Study
(2012-01-12)Vowel perception primarily depends on the overall shape of the speech spectrum, which is imposed by the positions of the primary speech articulators. Voiced vowels also have a harmonic fine structure due to the activity ... -
PERIODICITY ENVELOPE ENCODING: EVIDENCE FOR TWO SITES OF INTRODUCTION
(2015-04-06)The Envelope Following Response (EFR) has been under investigation as part of the ASSR evoked potential but it is unclear where exactly this periodicity envelope originates. The commonly accepted theory holds that the ... -
The Role of Altered Calcium-Handling in Mechanically-Induced Arrhythmias During Acute Regional Ischemia
(2016-06-27)Sudden Cardiac Death, a leading cause of death in Canada, commonly occurs as a result of arrhythmias occurring in the first hour of acute regional ischemia (ARI) after coronary artery occlusion. The mechanisms by which ARI ... -
THE ROLE OF MICROTUBULES IN ATRIAL MECHANO-ARRHYTHMOGENESIS
(2022-08-08)In the heart, electrical excitation causes mechanical contraction, while feedback of the heart’s mechanical state alters its electrical activity. With mechanical overload, this feedback can result in mechano-arrhythmogenesis ... -
THE ROLE OF TYRAMINE IN MODULATION OF SPIDER, CUPIENNIUS SALEI, MECHANORECEPTORS
(2015-04-29)Efferent neurons containing GABA, glutamate, acetylcholine and octopamine (OA) innervate spider, Cupiennius salei, mechanosensory neurons. The spider leg transcriptome library contains several putative transmitter receptors ...