Browsing Faculty of Graduate Studies Online Theses by Subject "Chemistry"
Now showing items 1-18 of 18
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Advances in Palladium and Nickel Catalyzed Cross-Coupling Reactions
(2017-12-13)Homogeneous organometallic complexes have become an indispensable tool as they are employed as catalysts for a large number of chemical transformations. Ancillary ligands, organic molecules that bind to the metal center, ... -
Core-Shell Materials as Positive Electrodes in Lithium-Ion Batteries
(2015-04-21)Electric vehicles with lithium-ion batteries as their energy storage technology have been sold by major automotive manufacturers for the past few years, but with limited sales. Sales are poor because of the high purchase ... -
Exploring Ligand-Enabled Nickel-Catalyzed Cross-Coupling of Sulfur-Based Nucleophiles
(2022-12-12)The catalytic synthesis of C(sp2)-N linkages is of utmost significance in modern synthetic chemistry, predominantly due to their prevalence in active pharmaceutical ingredients and natural products. Pd-catalyzed cross-couplings ... -
GLUTAMATE CATABOLISM AND SUCCINATE PRODUCTION IN Fusobacterium varium
(2017-08-08)Important bacteria located in the human gut contribute to human health and disease. Further understanding of metabolism in the gut bacterium F. varium was developed in this thesis. The use of [13C5]glutamate and the analysis ... -
Investigation of P-H, O-H, and Si-H Oxidative Addition Involving Group 9 Metal PSiP Complexes
(2020-08-07)Group 9 transition metal pincer complexes have shown remarkable reactivity with respect to E-H (E = main group element) bond activation chemistry. In this context, this research focuses on developing new Ir and Rh complexes ... -
Layered Oxide Phases for Sodium-ion Battery Electrodes
(2014-08-25)Sodium-ion batteries could offer an economical and environmentally friendly alternative to lithium-ion batteries, however many challenges must be overcome first. This project focused on the investigation of layered sodium ... -
Ligand-enabled advances in Ni-catalyzed cross-coupling
(2024-04-11)Due to their abundance in bioactive molecules, the construction of C(sp2)-X bonds (X = C, N, O) using cheap and abundant aryl electrophiles is centrally important in synthetic organic chemistry. Homogeneous catalysis has ... -
LIMITATIONS AND EXTENSIONS OF THE MAKISHIMA MACKENZIE MODEL
(2014-10-22)The Makishima Mackenzie model, used to predict the elastic properties of glass, is explored in terms of both accuracy and predictive properties. Its limitations are outlined, in particular for borate glass, and a new ... -
Mesomeric Tuning At Bi Centres & The Reuse Of A Waste Product From Cage Synthesis
(2022-12-06)Over the past decade, there has been a great interest in using the main group elements to do transition metal-like chemistry. Our research group installs ancillary ligands onto heavy main group elements, forcing them to ... -
Mesoporous Silicon Nanoparticles for Solar-Driven Hydrogen Generation from Water
(2021-12-13)Solar-driven hydrogen (H2) production from water (water splitting) by semiconductor photocatalysts has potential as a sustainable and cost-competitive alternative to current H2 production technologies. In recent years, ... -
A Preparative Route Investigation of N-Heterocyclic Phosphine Catalysts and their Application Towards the Synthesis of Colchinoid Analogues
(2020-12-14)A growing field in chemistry is the reduction of small molecules employing main group element catalysts. A recent advance has been the use of N-heterocyclic phosphines (NHPs) in the reduction of imines to produce secondary ... -
Small Molecule Activation Facilitated by Main Group Elements
(2021-08-30)Main group containing systems are emerging as an alternative to transition metal catalysts, often showing complementary reactivity. Transition metal complexes have provided the basis for fascinating catalytic reactions ... -
Study and Development of Synthetic Methodology Towards Pyrrolic Frameworks
(2021-01-07)This thesis focuses on the study and development of synthetic methodology towards pyrrolic frameworks. Three projects are discussed: the development of open-air conditions for the synthesis of F-BODIPYs, mechanistic studies ... -
Synthesis and Biological Evaluation of Prodigiosene Analogues
(2013-10-28)Prodigiosenes are a family of tripyrrolic 4-methoxypyrrolyl-dipyromethane natural products based on the parent compound, prodigiosin. Prodigiosin exhibits significant anti-cancer activity including some ability to specifically ... -
Synthesis of 2-aryl Pyrroles, Prodigiosene F-BODIPYs and B-ring Modified Prodigiosenes
(2019-12-16)Pyrrole constitutes the structural backbone of many natural products including heme and prodigiosin. This tripyrrolic natural product, and its synthetic analogues termed prodigiosenes, are reported to have an impressive ... -
Synthesis, Bonding, and Reactivity of Group 15 Amides
(2021-08-23)This thesis discusses the effects of ligand design on the chemistry of heavy Group 15 elements. The correlation of molecular geometry with frontier molecular orbital energies is a well-known principal. This principle was ... -
Thermal Contributions to Relative Free Energies of Allotropes and Polymorphs From Density-Functional Theory
(2022-04-14)Relative stabilities of two or more crystalline phases, such as allotropes or polymorphs, can be predicted theoretically using density-functional theory (DFT). Understanding the stability landscape of a given system has ... -
Towards the Synthesis of Di- and Tri-Pyrrolic Compounds
(2015)Dipyrrins and prodigiosenes are two classes of pyrrolic compounds. Dipyrrins consist of two pyrrole units linked by a methane bridge and prodigiosenes are a class of pyrrolyldipyrrins (a dipyrrin with a pyrrole substituent) ...