Browsing Faculty of Graduate Studies Online Theses by Subject "Cardiomyocyte"
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CHARACTERIZATION OF THE PHOSPHODIESTERASE SUBTYPES THAT REGULATE MOUSE ATRIAL MYOCYTE ELECTROPHYSIOLOGY
(2012-11-20)Phosphodiesterases (PDEs) are the enzymes responsible for the hydrolysis of cyclic nucleotides including cAMP and cGMP. We recently discovered that natriuretic peptides elicit effects in the atrial myocardium via a PDE ... -
THE ROLE OF MICROTUBULES IN ATRIAL MECHANO-ARRHYTHMOGENESIS
(2022-08-08)In the heart, electrical excitation causes mechanical contraction, while feedback of the heart’s mechanical state alters its electrical activity. With mechanical overload, this feedback can result in mechano-arrhythmogenesis ...