Browsing Faculty of Graduate Studies Online Theses by Subject "Cardiac development"
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INVESTIGATING THE TUMOUR SUPPRESSING ROLE OF HACE1 AND ITS NOVEL CONTRIBUTION TO CARDIAC DEVELOPMENT USING THE ZEBRAFISH MODEL
(2017-10-12)HACE1 is an E3 ubiquitin-ligase that is epigenetically downregulated in various malignancies. The mechanisms underlying its role in tumourigenesis and in normal vertebrate development have not been well elucidated. We ... -
The Role of Atrial Natriuretic Peptide Signalling in Ventricular Conduction System Development and Cardiac Function
(2023-08-23)The presence of a cardiac conduction defect in perinatal life increases the risk of heart failure. Studies have shown that atrial natriuretic peptide (ANP) and its high affinity receptor (NPRA) play a role in the formation ...