Browsing Faculty of Graduate Studies Online Theses by Subject "Cancer Biology"
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Oncolytic Reovirus Induces Intracellular Redistribution of Ras to Promote Apoptosis and Progeny Virus Release
(2014-08-22)Ras is a dynamic protein capable of interacting with plasma membrane microdomains and intracellular membranes. Its activity, as controlled by post-translational modifications, is essential in regulating cell growth, ... -
PRP4K IS A NOVEL HER2-REGULATED MODIFIER OF ANOIKIS AND TAXANE RESISTANCE
(2018-02-08)PRP4K is an essential kinase identified in Schizosaccharomyces pombe for its role in regulating pre-mRNA splicing. In addition to its role in splicing, mammalian PRP4K has also been implicated in mitotic checkpoint signaling, ...