Browsing Faculty of Graduate Studies Online Theses by Subject "Blood-brain barrier, cardiopulmonary bypass, p-glycoprotein, morphine"
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Surgery-induced inflammation reduces morphine distribution into cerebrospinal fluid
(2014-09-10)Background: Inflammation-induced alterations in drug disposition during inflammatory conditions such as infection and surgery are common and may lead to altered drug responses and/or toxicities. Animal studies have shown ...