Browsing by Subject "obesity"
Now showing items 1-7 of 7
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The Chemerin Receptor GPR1 Signals Through a RhoA/ROCK Pathway and Contributes to Glucose Homeostasis in Obese Mice
(2015-04-02)Chemerin is an adipose-derived hormone that regulates adipose tissue development, immunity, metabolism, and glucose homeostasis. To date, all chemerin function has been attributed to activation of the G protein-coupled ... -
Choice or Circumstance? An exploration of breastfeeding practice among Nova Scotian mothers classified as overweight or obese and income-related food insecure
(2017-02-27)Breastfeeding is a complex, relational practice spanning bio-physiological, social and structural considerations. Consistently, mothers across Nova Scotia report lower rates of breastfeeding initiation and duration of ... -
Forecasting Adult Weight Status Trends in Canada with Longitudinal Population-based Data
(2015-04-01)The prevalence of obesity in Canada and other Western countries has increased dramatically over the last 30 years. This project modelled future prevalence of weight status trends under a Markov framework by estimating ... -
IMPAIRED GHRELIN SECRETION IN OBESITY: THE KEY ROLE OF INSULIN RESISTANCE
(2020-09-11)Background: The stomach-derived hormone, ghrelin, has emerged as a key player in the neuro-endocrine regulation of appetite and energy storage. Ghrelin increases food intake and adiposity through its action on the ghrelin ... -
Obesity, physical activity and inflammation: Examining the development of ischemic heart disease among Nova Scotians
(2011-04-08)Background: CVD is a major cause of premature death in Nova Scotia, Canada. Objective: To determine the role of inflammation in the relationships between obesity, physical activity and IHD. Methods: Secondary analysis ... -
Patient Perspectives on Weight vs. Health-Centric Messaging around Obesity Management
(2024-08-10)Individuals living with obesity are often subject to weight-centric messaging in obesity management and treatment, which has been identified as contributing to weight bias and stigma, as well as unreasonable pressure to ... -
ROLE OF TRANSCRIPTION FACTOR EB (TFEB) IN CARDIAC HEALTH AND DISEASE
(2020-12-18)Cardiomyopathy is prevalent and the leading cause of mortality among obese and diabetic patients. Abnormalities in cardiac energy metabolism trigger myocyte dysfunction that precedes the onset of cardiomyopathy. Lack of ...