Browsing by Subject "Organic Chemistry"
Now showing items 1-5 of 5
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The Expression of 19F-Labeled Beta-Phosphoglucomutase and the Evaluation of Its Inhibitors
(2018-02-12)β-Phosphoglucomutase (βPGM) is an isomerase that catalyzes the conversion of β-glucose 1-phosphate to glucose 6-phosphate via a 1,6-bisphosphate intermediate. Incorporation of 5-fluorotryptophan (5FW) into βPGM (ie. ... -
FUNCTIONALIZATION OF MONO- AND DIPYRROLIC COMPOUNDS
(2017-02-02)Chemical manipulations of pyrrolic compounds can often prove to be difficult. This is especially true for dipyrrins. As a result of this, methodology development for the chemical manipulation of pyrrolic compounds is of ... -
Synthesis and Catalytic Activity of 1,2,4,3-Triazaphospholenes
(2018-04-04)Catalysis plays a key role in the industrial production of many refined goods. Catalysts derived from precious metals are especially prevalent in industry due to their high stereoselectivity, and low loadings. To alleviate ... -
Synthesis of Diazaphospholenes for Improved Catalysis
(2023-08-28)Diazaphospholene (DAP) synthesis and reactivity has been emerging over the last two decades. Recently, DAPs have been employed as catalysts for asymmetric reduction transformations. Specifically in the Speed group we use ... -
The Synthesis of Prodigiosene-Based Anticancer Reagents and Development of Reactions for Dipyrrin-Based Molecules
(2017-08-22)Prodigiosenes, dipyrrins and F-BODIPYs are related pyrrolic compounds that share a common, conjugated backbone structure composed of an adhered pyrrole and azafulvene unit. Prodigiosenes are tripyrrolic compounds isolated ...