Browsing by Subject "Enzyme"
Now showing items 1-2 of 2
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Computational Investigation into Catalytic Mechanisms of Disease-Causing Enzymes and Biocatalysts
(2015)Computational chemistry, namely the ONIOM method, is used to investigate areas of interest to drug design, including malaria and inflammation, as well as biocatalysts for the hydration of nitrile substrates. With the ... -
Design, Synthesis, and Evaluation of Thymidine Derivatives as Inhibitors of a Thymidylyltransferase Enzyme, Cps2L
(2020-08-06)The inhibition of thymidylyltransferase enzymes has long been studied as a potential avenue for antibiotic development. Several thymidine derivatives were designed, synthesized, and evaluated for binding and inhibition ...