Browsing by Subject "Demyelination"
Now showing items 1-3 of 3
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NEURONAL MITOCHONDRIAL CALCIUM UNIPORTER DEFICIENCY EXACERBATES AXONAL INJURY AND SUPPRESSES REMYELINATION IN MICE SUBJECTED TO EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
(2020-08-12)High-capacity mitochondrial calcium (Ca2+) uptake by the mitochondrial Ca2+ uniporter (MCU) is strategically positioned to support the survival and remyelination of axons in multiple sclerosis (MS) by undocking mitochondria, ... -
PIOGLITAZONE IS SUPERIOR TO QUETIAPINE, CLOZAPINE AND TAMOXIFEN AT ALLEVIATING EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
(2018-07-03)Recent evidence suggests that clozapine, quetiapine, tamoxifen and pioglitazone may improve functional recovery in multiple sclerosis (MS). We have compared the effectiveness of oral administration of these drugs, beginning ... -
REMYELINATION IS ACCELERATED BY EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS: A NOVEL MODEL FOR THE ELUCIDATION OF IMMUNE-MEDIATED BRAIN REPAIR
(2019-11-28)Introduction: Experimental autoimmune encephalomyelitis (EAE) and lysophosphatidylcholine (LPC)-induced demyelination are common rodent models of multiple sclerosis (MS). Clozapine and pioglitazone, two drugs used in the ...