Browsing by Subject "CREB-binding protein"
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Overexpressing Fragments of CREB-Binding Protein (CBP) to Block Transcriptional Dysregulation and Toxicity in Huntington's Disease
(2012-08-16)Huntington’s disease (HD) is caused by expression of the huntingtin gene containing an expanded CAG repeat. N-terminal mutant huntingtin protein (N-mHtt) accumulates in the nucleus and impairs transcription of a subset of ...