Browsing by Author "Johnston, G. C."
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FACT, the Bur kinase pathway, and the histone co-repressor HirC have overlapping nucleosome-related roles in yeast transcription elongation
Stevens, J. R.; O'Donnell, A. F.; Perry, T. E.; Benjamin, J. J. R.; Barnes, C. A.; Johnston, G. C.; Singer, R. A. (2011-2011/)Gene transcription is constrained by the nucleosomal nature of chromosomal DNA. This nucleosomal barrier is modulated by FACT, a conserved histone-binding heterodimer. FACT mediates transcription-linked nucleosome disassembly ... -
Mutational analysis of the Prt1 protein subunit of yeast translation initiation factor 3
Evans, D. R. H.; Rasmussen, C.; Hanic-Joyce, P. J.; Johnston, G. C.; Singer, R. A.; Barnes, C. A. (1995-/)The Saccharomyces cerevisiae PRT1 gene product Prt1p is a component of translation initiation factor eIF-3, and mutations in PRT1 inhibit translation initiation. We have investigated structural and functional aspects of ...