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Now showing items 11-20 of 33
Antimicrobial Activities of Jadomycin B and Structurally Related Analogues
(2009-03)
Natural products are leads for new antibiotics as a result of their structural complexity and
diversity. We have isolated a series of structurally related polyketide-derived natural products
from Streptomyces venezuelae ...
Elastase and Tryptase Govern TNF alpha-Mediated Production of Active Chemerin by Adipocytes
(2012-12)
Chemerin is a leukocyte chemoattractant and adipokine with important immune and metabolic roles. Chemerin, secreted in an inactive form prochemerin, undergoes C-terminal proteolytic cleavage to generate active chemerin, a ...
Development and validation of the Chinese version of the Reintegration to Normal Living Index for use with stroke patients
(2011-02)
OBJECTIVE: To develop and validate a Chinese version of the Reintegration to Normal
Living Index. DESIGN: Descriptive case-series. SUBJECTS: Seventy-five individuals with
chronic stroke and 55 age-matched healthy subjects. ...
Community engaged scholarship to catalyze innovation: a case study of the uptake of portable inhalers for respiratory medication in a pediatric emergency department in Nova Scotia
(Longwoods Publishing, 2016)
This commentary, in response to Tamblyn et al. (2016), provides a case study of the uptake of metered-dose inhalers with spacers to deliver respiratory medication in a pediatric emergency department in Nova Scotia. Our ...
A Method for Structure-Activity Analysis of Quorum-Sensing Signaling Peptides from Naturally Transformable Streptococci
(2009-12)
Many species of streptococci secrete and use a competence-stimulating peptide (CSP) to initiate
quorum sensing for induction of genetic competence, bacteriocin production, and other activities.
These signaling molecules ...
Exercise hemodynamic and neurohormone responses as sensitive biomarkers for diltiazem in rats
(2006-05)
Purpose. To investigate the potential of exercise hemodyanamic and neurohormone
variables as sensitive biomarkers for pre-clinical evaluation of diltiazem (DTZ).
Methods. Sprague Dawley (SD) rats were randomly divided ...
Evaluating the quality of randomized controlled trials that examine the efficacy of natural health products: a systematic review of critical appraisal instruments
(2009-12)
The purpose of this project was to conduct a systematic review to identify instruments designed to evaluate the quality of randomized controlled trials (RCTs) of natural health products (NHPs). Instruments were examined ...
Evaluating the quality of randomized controlled trials that examine the efficacy of natural health products: a systematic review of critical appraisal instruments
(2009-12)
The purpose of this project was to conduct a systematic review to identify instruments designed to evaluate the quality of randomized controlled trials (RCTs) of natural health products (NHPs). Instruments were examined ...
Impact of pharmacists as immunizers on vaccination rates: a systematic review and meta-analysis
(2016)
Background: Underutilization of vaccination programs remains a significant public health concern. Pharmacists serve as educators, facilitators, and in some jurisdictions, as administrators of vaccines. Though pharmacists ...
Measuring Knowledge Translation Uptake Using Citation Metrics: A Case Study of a Pan-Canadian Network of Pharmacoepidemiology Researchers
(Taylor & Francis, 2016)
ABSTRACT
Collecting citation metric data is important, as research funders
are increasingly demanding impact assessment, but there is
limited consensus on the most rigorous and accurate
approach. We compared three ...