A mild synthetic route to α-nitroso diaryl pyrroles (Postprint)
| dc.contributor.author | Brown, Emily B. | |
| dc.contributor.author | Gapare, Rosinah Liandrah | |
| dc.contributor.author | Campbell, Jacob W. | |
| dc.contributor.author | Alkaş, Adil | |
| dc.contributor.author | Sequeira, Steve | |
| dc.contributor.author | Hilborn, James W. | |
| dc.contributor.author | Greening, Sarah M. | |
| dc.contributor.author | Robertson, Katherine N. | |
| dc.contributor.author | Thompson, Alison | |
| dc.date.accessioned | 2024-09-10T18:29:11Z | |
| dc.date.available | 2024-09-10T18:29:11Z | |
| dc.date.issued | 2024 | |
| dc.identifier.citation | Published Version: Brown, E. B., Gapare, R. L., Campbell, J. W., Alkaş, A., Sequeira, S., Hilborn, J. W., ... & Thompson, A. (2024). A mild synthetic route to α-nitroso diaryl pyrroles. Organic & Biomolecular Chemistry, 22(30), 6122-6128. | en_US |
| dc.identifier.uri | http://hdl.handle.net/10222/84593 | |
| dc.description.abstract | A new synthetic method to access α-nitroso pyrroles is presented. This method utilises the nitrosonium salt NOBF4, enabling short reaction times (<10 minutes) and avoiding the harsh acidic conditions usually associated with pyrrole nitrosation. Application of this procedure to diarylated pyrroles yielded several novel nitroso-pyrroles. Modifications to the method, through exclusion of air and inclusion of a mild base, allowed for the nitrosation of pyrroles bearing aryl groups substituted with electron-donating groups. Attempts to nitrosylate pyrroles bearing alkyl substituents resulted in the formation of a dimeric material composed of a pyrrolic unit and a 2-hydroxyimino-protected 1,5-dihydro-2H-pyrrol-2-one. | en_US |
| dc.relation.ispartof | Organic & Biomolecular Chemistry | en_US |
| dc.title | A mild synthetic route to α-nitroso diaryl pyrroles (Postprint) | en_US |
| dc.type | Text | en_US |
