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The clinical meaningfulness of ADAS-Cog changes in Alzheimer’s disease patients treated with donepezil in an open-label trial
(BMC Springer Nature, 2007-08-30)
Background: In 6-month anti-dementia drug trials, a 4-point change in the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) is held to be clinically important. We examined how this change compared with ...
Assessment of factors associated with complete immunization coverage in children ages 12-23 months: A cross sectional study in Nouna district, Burkina Faso
(BMC Springer Nature, 2009-10-14)
Background: The Expanded Program on Immunization (EPI) is still in need of improvement. In Burkina Faso in 2003, for example, the Nouna health district had an immunization coverage rate of 31.5%, compared to the national ...
Frailty, fitness and late-life mortality in relation to chronological and biological age
(BMC Springer Nature, 2002-02-27)
Background: People age at remarkably different rates, but how to estimate trajectories of
senescence is controversial.
Methods: In a secondary analysis of a representative cohort of Canadians aged 65 and over (n = 2914) ...