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dc.contributor.authorDoyle, Jillian
dc.date.accessioned2017-08-21T17:17:25Z
dc.date.available2017-08-21T17:17:25Z
dc.identifier.urihttp://hdl.handle.net/10222/73127
dc.description.abstractA visual or olfactory stimulus (green light or phenylethyl alcohol) was presented to groups of adult zebrafish in their home tanks. An automatic feeder dispensed food immediately after the conditioned stimuli (CS), or at variable delays for controls. Fish showed anticipatory movement towards the food dispensing area after as few as 7-10 trials, learning that the CS was a predictor of food presentation at the water surface. Memories of the conditioned association persisted at least 2 days after training when fish were again presented with the CS. Control fish, for which the visual or olfactory stimuli were unpaired with food, showed no response when exposed to the CS. This simple, low-cost, automated system permits scalable conditioning of zebrafish with minimal human intervention, greatly reducing both variability and labour-intensiveness. It will be useful for studies of the neural basis of learning and memory, and for high-throughput screening of compounds modifying those processes.en_US
dc.language.isoenen_US
dc.subjectLearningen_US
dc.subjectMemoryen_US
dc.subjectAppetitiveen_US
dc.subjectParadigmen_US
dc.subjectZebrafishen_US
dc.subjectOlfactoryen_US
dc.subjectVisualen_US
dc.subjectHome Tanken_US
dc.subjectDanio rerioen_US
dc.titleAppetitive Learning Paradigm for Zebrafish (Danio rerio) in their Home Tanks Utilising Visual or Olfactory Cuesen_US
dc.date.defence2017-08-08
dc.contributor.departmentDepartment of Physiology & Biophysicsen_US
dc.contributor.degreeMaster of Scienceen_US
dc.contributor.external-examinerDr. Steven Barnesen_US
dc.contributor.graduate-coordinatorDr. Valerie Chappeen_US
dc.contributor.thesis-readerDr. Patrice Côtéen_US
dc.contributor.thesis-readerDr. Younes Aninien_US
dc.contributor.thesis-supervisorDr. Roger Crollen_US
dc.contributor.thesis-supervisorDr. Alan Fineen_US
dc.contributor.ethics-approvalReceiveden_US
dc.contributor.manuscriptsYesen_US
dc.contributor.copyright-releaseYesen_US
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