Browsing Pediatrics Faculty Research, Publications and Presentations by Submit Date

Now showing items 21-34 of 34

  • Assessment of factors associated with complete immunization coverage in children ages 12-23 months: A cross sectional study in Nouna district, Burkina Faso 

    Sanou, A., Simboro, S., Kouyaté, B., Dugas, M., Graham, J., & Bibeau, G. (2009). Assessment of factors associated with complete immunization coverage in children aged 12-23 months: a cross-sectional study in Nouna district, Burkina Faso. BMC International Health and Human Rights, 9(Suppl 1), S10. doi: 10.1186/1472-698X-9-S1-S10
    Background: The Expanded Program on Immunization (EPI) is still in need of improvement. In Burkina Faso in 2003, for example, the Nouna health district had an immunization coverage rate of 31.5%, compared to the national ...

  • The clinical meaningfulness of ADAS-Cog changes in Alzheimer’s disease patients treated with donepezil in an open-label trial 

    Rockwood, K., Fay, S., Gorman, M., Carver, D., & Graham, J. E. (2007). The clinical meaningfulness of ADAS-Cog changes in Alzheimer's disease patients treated with donepezil in an open-label trial. BMC Neurology, 7(1), 26. doi:10.1186/1471-2377-7-26
    Background: In 6-month anti-dementia drug trials, a 4-point change in the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) is held to be clinically important. We examined how this change compared with ...

  • Frailty, fitness and late-life mortality in relation to chronological and biological age 

    Mitnitski, A. B., Graham, J. E., Mogilner, A. J., & Rockwood, K. (2002). Frailty, fitness and late-life mortality in relation to chronological and biological age. BMC Geriatrics, 2, 1. https://doi.org/10.1186/1471-2318-2-1
    Background: People age at remarkably different rates, but how to estimate trajectories of senescence is controversial. Methods: In a secondary analysis of a representative cohort of Canadians aged 65 and over (n = 2914) ...

  • Do health care providers trust product monograph information regarding use of vaccines in pregnancy? A qualitative study 

    Top KA, Arkell C, Graham JE, Scott H, McNeil SA, Mannerfeldt J, NE MacDonald. Do health care providers trust product monograph information regarding use of vaccines in pregnancy? A qualitative study. Can Commun Dis Rep 2018;44(6):134-8. https://doi.org/10.14745/ccdr.v44i06a03
    Background: In uenza immunization is recommended in pregnancy to prevent severe infections in pregnant women and newborns, yet vaccine uptake remains low. Studies suggest that cautionary language in vaccine product monographs ...

  • Lueurs et leurres de la santé globale À propos de MenAfriVac®, un vaccin « africain » contre la méningite 

    Thiongane, O., Graham, J. E., & Broutin, H. (2017). Lueurs et leurres de la santé globale: À propos de MenAfriVac®, un vaccin « africain » contre la méningite. Anthropologie & développement, 46-47(2017), 213-234 . doi: 10.4000/anthropodev.607
    In biomedical narratives, the Meningitis Vaccine Project (MVP) enabled the technology transfer for the development and implementation of MenAfriVac® vaccine at an affordable price for African countries. The presentation ...

  • Understanding vaccine hesitancy in Canada: Results of a consultation study by the Canadian Immunization Research Network 

    Dubé, E., Gagnon, D., Ouakki, M., Bettinger, J. A., Guay, M., Halperin, S., ... & Fisher, W. (2016). Understanding vaccine hesitancy in Canada: Results of a consultation study by the Canadian Immunization Research Network. PloS one, 11(6), e0156118. doi: 10.1371/journal.pone.0156118
    “Vaccine hesitancy” is a concept now frequently used in vaccination discourse. The increased popularity of this concept in both academic and public health circles is challenging previously held perspectives that individual ...

  • Ambiguous Capture: Collaborative Capitalism and the Meningitis Vaccine Project 

    Graham, J. E. (2016). Ambiguous capture: Collaborative capitalism and the meningitis vaccine project. Medical anthropology, 35(5), 419-432. doi:10.1080/01459740.2016.1167055
    The primary health care approach advanced at Alma Ata to address social determinants of health was replaced by selective health care a year later at Bellagio. Subsequently, immunization was endorsed as a cost-effective ...

  • Exploring the post-genomic world: differing explanatory and manipulatory functions of post-genomic sciences 

    Holmes, C., Carlson, S. M., McDonald, F., Jones, M., & Graham, J. E. (2016). Exploring the post-genomic world: Differing explanatory and manipulatory functions of post-genomic sciences. New Genetics and Society, 35(1), 49-68. doi: 10.1080/14636778.2015.1133280
    Richard Lewontin proposed that the ability of a scientific field to create a narrative for public understanding garners it social relevance. This article applies Lewontin’s conceptual framework of the functions of science ...

  • Risks of nutrigenomics and nutrigenetics? What the scientists say. 

    Hurlimann, T., Menuz, V., Graham, J., Robitaille, J., Vohl, M. C., & Godard, B. (2014). Risks of nutrigenomics and nutrigenetics? What the scientists say. Genes & nutrition, 9(1), 370. DOI 10.1007/s12263-013-0370-6
    Nutrigenomics and nutrigenetics (hereafter NGx) have stimulated expectations for beneficial applications in public health and individuals. Yet, the potential achievability of such promise is not without socioethical ...

  • Faster access to new drugs: Fault lines between Health Canada’s regulatory intent and Industry innovation practices 

    Graham, J. E., & Nuttall, R. K. (2013). Faster access to new drugs: Fault lines between Health Canada’s regulatory intent and Industry innovation practices. Ethics in Biology, Engineering and Medicine: An International Journal, 4(3), 231-239. DOI: 10.1615/EthicsBiologyEngMed.2014010771.
    Since 2003, Health Canada has been undergoing regulatory modernization to “ensure that Canadians have faster access to the safe drugs they need.” As national health agencies develop policies to modernize the regulation ...

  • Just Evidence: Opening Health Knowledge to a Parliament of Evidence 

    Graham, J. E., & Jones, M. (2016). Just Evidence: Opening Health Knowledge to a Parliament of Evidence. In B. H. MacDonald, S. S. Soomai, E. M. De Santo, & P. G. Wells (Eds.), Science, Information, and Policy Interface for Effective Coastal and Ocean Management (pp. 362-387). CRC Press.
    In this chapter, we present a complementary perspective to the oceans theme of this volume by ethnographically engaging the circulation of scientific knowledge and evidence in a different but comparable policy decision-making ...

  • Birth weight for gestational age and the risk of asthma in childhood and adolescence: a retrospective cohort study 

    Carter JH, Woolcott CG, Liu L, Kuhle S. Birth weight for gestational age and the risk of asthma in childhood and adolescence: a retrospective cohort study. Arch Dis Child. 2019 Feb;104(2):179-183. http://dx.doi.org/10.1136/archdischild-2018-315059. Epub 2018 Jul 19. PMID: 30026251.
    Objective: To examine the association between birthweight for gestational age and asthma in childhood and adolescence while controlling for potential confounders and considering smoking as an effect modifier. Methods: A ...

  • Maternal pre-pregnancy weight status and health care use for mental health conditions in the offspring 

    Grudzinski A, Campbell LA, Liu L, Brown MM, Dodds L, Kuhle S. Maternal pre-pregnancy weight status and health care use for mental health conditions in the offspring. Eur Child Adolesc Psychiatry. 2019 Nov;28(11):1499-1506. https://doi.org/10.1007/s00787-019-01312-w. Epub 2019 Mar 18. PMID: 30887130.
    Objectives: The objective of this study was to examine the relationship between pre-pregnancy maternal weight status and offspring physician visits for mental health conditions in childhood and adolescence. Methods: We ...

  • Cesarean Delivery and Healthcare Utilization and Costs in the Offspring: A Retrospective Cohort Study 

    MacLellan AN, Woolcott CG, Brown MM, Dodds L, McDonald SD, Kuhle S. Cesarean Delivery and Healthcare Utilization and Costs in the Offspring: A Retrospective Cohort Study. J Pediatr. 2019 Jun;209:61-67.e2. https://doi.org/10.1016/j.jpeds.2019.02.031. Epub 2019 Apr 2. PMID: 30952508.
    Objective: To examine the association between Caesarean section (CS) and health care utilization and costs in offspring from birth until age 7 years. Methods: A retrospective cohort study of singleton term births in the ...